Evidence map›Paper›PMID 29785258›Full record

ArticleJournal of tissue engineering

Intra-articular biomaterials-assisted delivery to treat temporomandibular joint disorders.

Khandmaa Dashnyam, Jung-Hwan Lee, Nandin Mandakhbayar, Guang-Zhen Jin, Hae-Hyoung Lee, Hae-Won Kim

Open access · goldAbstract read
In one paragraph

Article in Journal of tissue engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 50 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Khandmaa DashnyamInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, South Korea.
Jung-Hwan LeeInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, South Korea.
Nandin MandakhbayarInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, South Korea.
Guang-Zhen JinInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, South Korea.
Hae-Hyoung LeeInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, South Korea.
Hae-Won KimInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, South Korea.
Dankook University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The temporomandibular joint disorder, also known as myofascial pain syndrome, is considered one of the prevalent chronic pain diseases caused by muscle inflammation and cartilage degradation in head and neck, and thus influences even biopsychosocial conditions in a lifetime. There are several current treatment methodologies relieving inflammation and preventing degradation of the joint complex. One of the promising non-surgical treatment methods is an intra-articular injection of drugs such as corticosteroids, analgesics, and anti-depressants. However, the side effects of drugs due to frequent injections and over-doses, including dizziness, dry mouth, and possible drug dependency are considered limitations. Thus, the delivery of therapeutic molecules through the use of nano/microparticles is currently considered as a promising strategy primarily due to the controlled release. This review highlights the nano/microparticle systems for effective intra-articular therapeutics delivery to prevent cartilage degradation and protect subchondral bone in a temporomandibular joint.

Indexed as

intra-articular injectionmyofascial pain syndromenano/microparticlesTemporomandibular jointtemporomandibular joint disordertherapeutics delivery

Identifiers

PMID29785258
PMCPMC5954570
OpenAlexW2804619016

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.