Evidence map›Paper›PMID 29785199›Full record

ReviewClinical practice and epidemiology in mental health : CP & EMH2018

Physical Exercise For Parkinson's Disease: Clinical And Experimental Evidence.

Alessandro Oliveira de Carvalho, Alberto Souza Sá Filho, Eric Murillo-Rodriguez, Nuno Barbosa Rocha, Mauro Giovanni Carta, Sergio Machado

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Clinical practice and epidemiology in mental health : CP & EMH, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 7 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 7 syntheses or guidelines pooled it, 107 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Effects of a gait training program with the FisiorBMC complementary medicine and therapies · 2026
    Trial
  9. Trial
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Alessandro Oliveira de CarvalhoInstitute of Psichiatry, Federal University of Rio de Janeiro (IPUB/UFRJ), Rio de Janeiro, Brazil.
Alberto Souza Sá FilhoInstitute of Psichiatry, Federal University of Rio de Janeiro (IPUB/UFRJ), Rio de Janeiro, Brazil.
Eric Murillo-RodriguezPolitechnique Institute of Porto, Healthy School, Porto, Portugal.
Nuno Barbosa RochaPolitechnique Institute of Porto, Healthy School, Porto, Portugal.
Mauro Giovanni CartaLaboratorio de Neurociencias Moleculares e Integrativas Escuela de Medicina, División Ciencias de la Salud Universidad Anáhuac Mayab, Yucatán, Mexico.
Sergio MachadoPhysical Activity Neuroscience, Physical Activity Sciences Postgraduate Program - Salgado de Oliveira University, Niterói, Brazil.
Polytechnic Institute of Porto · PTAnahuac Mayab University · MXUniversidade Castelo Branco · BRUniversidade Estadual de Campinas (UNICAMP) · BRUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNational projections about the increase in the elderly population over 60 years bring with it an increase in the number of people affected by Parkinson's Disease (PD), making it an important public health problem. Therefore, the establishment of effective strategies for intervention in people with PD needs to be more clearly investigated.

objectiveThe study aimed to report the effectiveness of exercise on functional capacity and neurobiological mechanisms in people with PD.

methodsThis study is a critical review of the literature.

resultsThe progressive death of dopaminergic neurons in the substantia nigra is described as one of the main physiological mechanisms manifested before PD, directly interfering with motor behavior. However, PD is not only related to motor symptoms, but also to cognitive, autonomic, and mood impairments. Such effects may be attenuated by pharmacological influence, but also evidence suggests that the implementation of regular physical exercise programs may exhibit potential benefits over PD. The synthesis and expression of monoaminergic neurotransmitters can act positively on motor disorders, as well as directly or indirectly influence the neuronal plasticity of the brain, restoring neuronal pathways previously affected.

conclusionPhysical exercise contributes effectively to the treatment of PD, and can play a preventive and maintenance role of physical fitness and mental health.

Indexed as

Aerobic exerciseBrain-derived neurotrophic factorMood impairmentParkinson’s diseasePhysical fitnessStrength training

Identifiers

PMID29785199
PMCPMC5897963
OpenAlexW2795157884

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.