Evidence map›Paper›PMID 29785196›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2018

A Computational Approach Using Bioinformatics to Screening Drug Targets for

Miguel Angel Chávez-Fumagalli, Mônica Santos Schneider, Daniela Pagliara Lage, Grasiele de Sousa Vieira Tavares, Débora Vasconcelos Costa Mendonça, Thaís Teodoro de Oliveira Santos, Rodrigo Maia Pádua, Ricardo Andrez Machado-de-Ávila, João Paulo Viana Leite, Eduardo Antonio Ferraz Coelho

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. In Vivo Glycemic Response of Fruit-Based Mango (Foods (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. SystematicFrontiers in chemistry · 2021
    Article
  8. Frontiers in genetics · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Miguel Angel Chávez-FumagalliPrograma de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Mônica Santos SchneiderPrograma de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Daniela Pagliara LagePrograma de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID 0000-0002-8710-9265
Grasiele de Sousa Vieira TavaresPrograma de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Débora Vasconcelos Costa MendonçaPrograma de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Thaís Teodoro de Oliveira SantosPrograma de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Rodrigo Maia PáduaDepartamento de Produtos Farmacêuticos, Faculdade de Farmácia, Universidade Federal de Minas Gerais, 31.270-901 Belo Horizonte, MG, Brazil.
Ricardo Andrez Machado-de-ÁvilaPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.
João Paulo Viana LeiteDepartamento de Bioquímica e Biologia Molecular, Universidade Federal de Viçosa, 36.570-000 Viçosa, MG, Brazil.ORCID 0000-0002-3747-4424
Eduardo Antonio Ferraz CoelhoPrograma de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID 0000-0002-6681-9014
Universidade Federal de Minas Gerais · BRUniversidade do Extremo Sul Catarinense · BRUniversidade Federal de Viçosa · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe development of new therapeutic strategies to treat patients for leishmaniasis has become a priority. The antileishmanial activity of the strychnobiflavone flavonoid was recently demonstrated against METHODS AND

resultsIn this study, a computational approach using bioinformatics was performed to screen biological targets of strychnobiflavone in

conclusionIn this context, this study provides the basis for understanding the mechanism of action of strychnobiflavone in

Identifiers

PMID29785196
PMCPMC5896251
OpenAlexW2795188988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.