Evidence map›Paper›PMID 29785100›Full record

SynthesisInternational journal of chronic obstructive pulmonary disease2018

Gender-specific estimates of COPD prevalence: a systematic review and meta-analysis.

Georgios Ntritsos, Jacob Franek, Lazaros Belbasis, Maria A Christou, Georgios Markozannes, Pablo Altman, Robert Fogel, Tobias Sayre, Evangelia E Ntzani, Evangelos Evangelou

2 registry-linked trialsOpen access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in International journal of chronic obstructive pulmonary disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 137 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed, 9 pooled it
12.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04357743 nacompletednot on this mapstarted 2019, after this paper: background citation

Effects of Pursed Lip Breathing With Arm Ergometry After Chin Supported Position in COPD Patients.

TypeinterventionalSponsorRiphah International UniversityRan2019 to 2020Enrolled74ConditionsCOPDArmsChin supported Arm ergometry with pursed lip breathing, Arm ergometry with pursed lip breathing
NCT05424133 nacompletednot on this mapstarted 2022, after this paper: background citation

Comparative Effects of Active Cycle of Breathing Technique and High Frequency Chest Wall Oscillation in Chronic Obstructive Pulmonary Disease Patients

TypeinterventionalSponsorRiphah International UniversityRan2022 to 2022Enrolled42ConditionsChronic Obstructive Pulmonary DiseaseArmsHigh frequency chest wall oscillation, Active cycle of breathing
3 · Its place in the literature

Who cites it

137 citing papers in PubMed, 9 syntheses or guidelines pooled it, 251 citations in OpenAlex.

  1. Muscle sympathetic nerve activity in COPD: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2026
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  20. A Proposed Checklist for Optimizing COPD Patient Discharge Processes in Italian Internal Medicine Wards.International journal of chronic obstructive pulmonary disease · 2026
    Review

77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Georgios NtritsosClinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece.
Jacob FranekDoctor Evidence, Client Solutions, Santa Monica, CA, USA.
Lazaros BelbasisClinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece.
Maria A ChristouClinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece.
Georgios MarkozannesClinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece.
Pablo AltmanGlobal Medical Affairs, Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA.
Robert FogelGlobal Medical Affairs, Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA.
Tobias SayreDoctor Evidence, Client Solutions, Santa Monica, CA, USA.
Evangelia E NtzaniClinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece.
Evangelos EvangelouClinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece.
University of Ioannina · GRNovartis (United States) · USPDF Solutions (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rationale: COPD has been perceived as being a disease of older men. However, >7 million women are estimated to live with COPD in the USA alone. Despite a growing body of literature suggesting an increasing burden of COPD in women, the evidence is limited. Objectives: To assess and synthesize the available evidence among population-based epidemiologic studies and calculate the global prevalence of COPD in men and women. Materials and methods: A systematic review and meta-analysis reporting gender-specific prevalence of COPD was undertaken. Gender-specific prevalence estimates were abstracted from relevant studies. Associated patient characteristics as well as custom variables pertaining to the diagnostic method and other important epidemiologic covariates were also collected. A Bayesian random-effects meta-analysis was performed investigating gender-specific prevalence of COPD stratified by age, geography, calendar time, study setting, diagnostic method, and disease severity. Measurements and main results: Among 194 eligible studies, summary prevalence was 9.23% (95% credible interval [CrI]: 8.16%-10.36%) in men and 6.16% (95% CrI: 5.41%-6.95%) in women. Gender prevalences varied widely by the World Health Organization Global Burden of Disease subregions, with the highest female prevalence found in North America (8.07% vs 7.30%) and in participants in urban settings (13.03% vs 8.34%). Meta-regression indicated that age ≥40 and bronchodilator testing contributed most significantly to heterogeneity of prevalence estimates across studies. Conclusion: We conducted the largest ever systematic review and meta-analysis of global prevalence of COPD and the first large gender-specific review. These results will increase awareness of COPD as a critical woman's health issue.

Indexed as

Global HealthAdolescentAdultAgedAge DistributionFemaleHumansMaleMiddle AgedPredictive Value of TestsPrevalencePulmonary Disease, Chronic ObstructiveRespiratory Function TestsRisk FactorsSeverity of Illness IndexSex DistributionageCOPDgendermeta-analysisprevalencesystematic review

Identifiers

PMID29785100
PMCPMC5953270
OpenAlexW2801636811

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.