ArticleJournal of perinatology : official journal of the California Perinatal Association2018
Effects of maternal obstructive sleep apnea on fetal growth: a case-control study.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Fetal and neonatal outcomes of pregnancies complicated by maternal sleep-disordered breathing: a systematic review.Frontiers in physiology · 2026Pooled it
- Maternal sleep disordered breathing and offspring growth outcome: A systematic review and meta-analysis.Sleep medicine reviews · 2024Pooled it
- Pooled it
- Influence of Obstructive Sleep Apnea on Maternal and Perinatal Outcomes in Patients With Gestational Diabetes Mellitus.Journal of sleep research · 2026Article
- Preliminary Evidence Linking Maternal Sleep-Disordered Breathing During Pregnancy to Early Childhood Development: A 3-Year Pilot Cohort Study in Japan.Children (Basel, Switzerland) · 2025Article
- Influence of Obstructive Sleep Apnea on Oxidative Stress in Pregnancy.International journal of molecular sciences · 2025Article
- Obstructive Sleep Apnea in Pregnancy and its Impact on Maternal-Fetal Health: A Hidden Threat - Narrative Review.The open respiratory medicine journal · 2025Review
- Effect of Obstructive Sleep Apnea during Pregnancy on Fetal Development: Gene Expression Profile of Cord Blood.International journal of molecular sciences · 2024Article
- Gestational intermittent hypoxia reduces mandibular growth with decreasedFrontiers in physiology · 2024Article
- Association between sleep disturbances during pregnancy and adverse perinatal outcomes.American journal of translational research · 2024Article
- A Relation between Obstructive Sleep Apnea in Pregnancy and Delivering Small for Gestational Age Infant-A Systematic Review.Journal of clinical medicine · 2023Review
- Common sleep disorders in pregnancy: a review.Frontiers in medicine · 2023Review
- Burden of sleep disturbance in non-Hispanic Black pregnant women.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Fetal growth restriction and stillbirth: Biomarkers for identifying at risk fetuses.Frontiers in physiology · 2022Review
- Fetal Heart Rate Decelerations in Women with Sleep-Disordered Breathing.Reproductive sciences (Thousand Oaks, Calif.) · 2021Article
- Snoring and depression symptoms in pregnant women.Sleep health · 2021Article
- Sleep-disordered breathing in pregnancy: a developmental origin of offspring obesity?Journal of developmental origins of health and disease · 2021Review
- Maternal obstructive sleep apnea and neonatal birth outcomes in a population based sample.Sleep medicine · 2020Article
- Article
- Intermittent hypoxia impairs uterine artery function in pregnant mice.The Journal of physiology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo investigate whether maternal obstructive sleep apnea (OSA) is associated with changes in fetal growth trajectory. STUDY
designRetrospective review of pregnant women who underwent overnight polysomnography. Fetal growth was estimated using sonographic biometric measurements obtained during routine prenatal care. Customized estimated fetal weight and birth weight centiles were calculated and impaired fetal growth was defined as birth weight <10th centile or a slowing of fetal growth by >33% during the last trimester. Logistic regression models were used to determine the relationship between maternal OSA and altered fetal growth after adjusting for potential covariates.
resultsThere were 48 women without and 31 women with OSA. There were no differences in the proportion of infants with birth weight <10th centile between women with and without OSA (23 vs. 25%, p = 1.0), However, the presence of maternal OSA was predictive of impaired fetal growth (aOR 3.9, 95% CI 1.2-12.6). Logistic regression models were repeated using only a slowing of fetal growth in the 3rd trimester (excluding birth weight <10th centile) and OSA predicted a slowing in fetal growth across the 3rd trimester (aOR 3.6, 95% CI 1.4-9.4). Fourteen additional women were treated with positive airway pressure during pregnancy; fetal growth was not significantly different in these women compared to controls.
conclusionObstructive sleep apnea is independently associated with altered fetal growth, which appears to be ameliorated with use of positive airway pressure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.