ArticleScientific reports2018
Mindfulness training induces structural connectome changes in insula networks.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04073940 (Exploration of Brain Changes Due to a Targeted Ballet Program in Multiple Sclerosis), which is not on this map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Exploration of Brain Changes Due to a Targeted Ballet Program in Multiple Sclerosis
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review exploring the association between the human gut microbiota and brain connectivity in health and disease.Molecular psychiatry · 2023Pooled it
- Do mindfulness-based interventions change brain function in people with substance dependence? A systematic review of the fMRI evidence.BMC psychiatry · 2023Pooled it
- Hunyuan zhuang improves interoception: evidence from an expert-novice study and a pilot randomized controlled trial.Scientific reports · 2026Trial
- The impact of a brief mindfulness training on interoception: A randomized controlled trial.PloS one · 2022Trial
- The Role of Heart Rate Variability in Mindfulness-Based Pain Relief.The journal of painTrial
- Machine learning reveals a multimodal, transdiagnostic signature of emotion dysregulation vulnerability across patients, offspring, and controls.Molecular psychiatry · 2026Article
- Meditation in Motion: Sport Type and Meditation Level Shape Gut Microbiota Profiles in Aikido and Tai Chi Practitioners.Microorganisms · 2026Article
- Burnout and the Brain-A Mechanistic Review of Magnetic Resonance Imaging (MRI) Studies.International journal of molecular sciences · 2025Review
- Unlocking deep relaxation: the power of rhythmic breathing on brain rhythms.Npj mental health research · 2025Article
- The Left Insula Bridges Cognition, Emotion, and Brain Structure: A Multilayer Network Analysis of the Human Connectome Project-Young Adult.bioRxiv : the preprint server for biology · 2025Article
- Mental gravity as a translational framework for mental health promotion.Frontiers in human neuroscience · 2025Article
- Subjective Time in Ordinary and Non-ordinary States of Consciousness: How Interoceptive Feelings Inform Us About the Passage of Time.Current topics in behavioral neurosciences · 2025Review
- Article
- How to create a mindful community of practice: exploring the social functions of group-based mindfulness practices facilitated via Zoom during COVID-19.Frontiers in psychology · 2025Article
- Tai Chi Practice Buffers Aging Effects in Functional Brain Connectivity.Brain sciences · 2024Article
- Do Individual Differences in Perception Affect Awareness of Climate Change?Brain sciences · 2024Article
- Meditation and interoception: a conceptual framework for the narrative and experiential self.Frontiers in psychology · 2024Review
- Interoceptive brain network mechanisms of mindfulness-based training in healthy adolescents.Frontiers in psychology · 2024Article
- Effects of acceptance and commitment therapy on cognitive function: A systematic review.Heliyon · 2023Review
- The effect of mindfulness-based intervention on neurobehavioural functioning and its association with white-matter microstructural changes in preterm young adolescents.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Although mindfulness meditation is known to provide a wealth of psychological benefits, the neural mechanisms involved in these effects remain to be well characterized. A central question is whether the observed benefits of mindfulness training derive from specific changes in the structural brain connectome that do not result from alternative forms of experimental intervention. Measures of whole-brain and node-level structural connectome changes induced by mindfulness training were compared with those induced by cognitive and physical fitness training within a large, multi-group intervention protocol (n = 86). Whole-brain analyses examined global graph-theoretical changes in structural network topology. A hypothesis-driven approach was taken to investigate connectivity changes within the insula, which was predicted here to mediate interoceptive awareness skills that have been shown to improve through mindfulness training. No global changes were observed in whole-brain network topology. However, node-level results confirmed a priori hypotheses, demonstrating significant increases in mean connection strength in right insula across all of its connections. Present findings suggest that mindfulness strengthens interoception, operationalized here as the mean insula connection strength within the overall connectome. This finding further elucidates the neural mechanisms of mindfulness meditation and motivates new perspectives about the unique benefits of mindfulness training compared to contemporary cognitive and physical fitness interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.