SynthesisInternational journal of impotence research2018
Relation between hypertension and erectile dysfunction: a meta-analysisof cross-section studies.
Synthesis in International journal of impotence research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Erectile dysfunction following prostate biopsy: a comparative analysis of transrectal versus transperineal approaches.International urology and nephrology · 2026Pooled it
- Metabolic syndrome and erectile dysfunction: a systematic review and meta-analysis study.Journal of endocrinological investigation · 2023Pooled it
- Male sexual dysfunction associated with TNF-α inhibitors: an indication-stratified global pharmacovigilance analysis.Frontiers in pharmacology · 2026Article
- Associations between metabolic syndrome and erectile dysfunction: evidence from the NHANES 2001-2004.Frontiers in public health · 2025Article
- Prevalence of Erectile Dysfunction and its Psychological Impact on Patients with Ischaemic Heart Disease in Oman.Sultan Qaboos University medical journal · 2025Article
- Association between telomere length and erectile dysfunction: a cross-sectional study.Frontiers in endocrinology · 2024Article
- Genetically predicted cardiovascular diseases could increase the risk of erectile dysfunction: a bidirectional Mendelian randomization.World journal of urology · 2023Article
- Review
- Contemporary cost-analysis comparison of direct-to-consumer vs. traditional prescriptions of phosphodiesterase-5 inhibitors.International journal of impotence research · 2023Article
- The Italian Society of Andrology and Sexual Medicine (SIAMS), along with ten other Italian Scientific Societies, guidelines on the diagnosis and management of erectile dysfunction.Journal of endocrinological investigation · 2023Article
- Mechanisms Suggesting a Relationship between Vitamin D and Erectile Dysfunction: An Overview.Biomolecules · 2023Review
- Quality of life of hypertensive men with erectile dysfunction in a tertiary health centre in southern Nigeria.African journal of primary health care & family medicine · 2023Article
- Psychosocial risk factors of erectile dysfunction among heterosexual men living with HIV.AIDS care · 2023Article
- Relationship Between Hypertension, Antihypertensive Drugs and Sexual Dysfunction in Men and Women: A Literature Review.Vascular health and risk management · 2023Review
- Causal effects of hypertension on risk of erectile dysfunction: A two-sample Mendelian randomization study.Frontiers in cardiovascular medicine · 2023Article
- Magnitude of impaired fasting glucose and undiagnosed diabetic mellitus and associated risk factors among adults living in Woreta town, northwest Ethiopia: a community-based cross-sectional study, 2021.BMC endocrine disorders · 2022Article
- Exercise, Erectile Dysfunction and Co-Morbidities: "The Good, the Bad and the Ugly".Reviews in cardiovascular medicine · 2022Review
- Knowledge, attitude, and practice (KAP) regarding erectile dysfunction disease and its medications among community pharmacy technicians in Mogadishu Somalia.Annals of medicine and surgery (2012) · 2022Article
- Association between erectile dysfunction, cardiovascular risk factors, and coronary artery disease: Role of exercise stress testing and International Index of Erectile Function (IIEF-5) questionnaire.International journal of cardiology. Heart & vasculature · 2022Article
- A Natural History of Erectile Dysfunction in Elderly Men: A Population-Based, Twelve-Year Prospective Study.Journal of clinical medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Erectile dysfunction (ED) is a wide spread and troublesome problem in aging men. Many analyses of hypertensive patients suggest that the prevalence of ED in hypertensive populations is even higher. The purpose of this meta-analysis was to evaluate the relation between hypertension and ED. A literature review was performed to identify all cross-section studies about hypertension and erectile dysfunction. Sources included MEDLINE and EMBASE from 1966 to 2015. The reference lists of the retrieved studies were also investigated, and a meta-analysis were conducted. Eighteen cross-section studies involving a total of 41,943 participants and 10,151 cases of ED were used in this analysis. We found that risk of ED was increased with hypertension (summary OR = 1.84, 95% CI: 1.58-2.14, p < 0.000001). Adjusting for obesity, unfavorable lipid levels, alcohol abuse, physical activity, cigarette smoking, educational level and other lifestyle factors, hypertension was also associated with increased risk of ED (summary OR = 1.58, 95% CI: 1.35-1.86, p < 0.00001). The results of this meta-analysis support that hypertension is associated with an increased risk of ED. Further high-quality prospective studies are needed to confirm this observation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.