Evidence map›Paper›PMID 29784956›Full record

ReviewNature reviews. Molecular cell biology2018

Dynamics and function of DNA methylation in plants.

Huiming Zhang, Zhaobo Lang, Jian-Kang Zhu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Molecular cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 850 papers.

0numbers the graph read from it
0cells of the map it votes in
850citing papers in PubMed
196.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

850 citing papers in PubMed, 1,792 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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  6. Review
  7. Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  8. International journal of molecular sciences · 2026
    Article
  9. Article
  10. Review
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  15. Review
  16. Fluorescent Analysis of KBiomolecules · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. Article

790 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Huiming ZhangShanghai Center for Plant Stress Biology, Chinese Academy of Sciences, Shanghai, China. hmzhang@sibs.ac.cn.
Zhaobo LangShanghai Center for Plant Stress Biology, Chinese Academy of Sciences, Shanghai, China.
Jian-Kang ZhuShanghai Center for Plant Stress Biology, Chinese Academy of Sciences, Shanghai, China. jkzhu@sibs.ac.cn.ORCID 0000-0001-5134-731X
Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA methylation is a conserved epigenetic modification that is important for gene regulation and genome stability. Aberrant patterns of DNA methylation can lead to plant developmental abnormalities. A specific DNA methylation state is an outcome of dynamic regulation by de novo methylation, maintenance of methylation and active demethylation, which are catalysed by various enzymes that are targeted by distinct regulatory pathways. In this Review, we discuss DNA methylation in plants, including methylating and demethylating enzymes and regulatory factors, and the coordination of methylation and demethylation activities by a so-called methylstat mechanism; the functions of DNA methylation in regulating transposon silencing, gene expression and chromosome interactions; the roles of DNA methylation in plant development; and the involvement of DNA methylation in plant responses to biotic and abiotic stress conditions.

Indexed as

AnimalsArabidopsisArabidopsis ProteinsDNA MethylationDNA, PlantEpigenesis, GeneticGene Expression Regulation, PlantHumansNuclear ProteinsPlantsArabidopsis ProteinsDNA, PlantNuclear ProteinsROS1 protein, Arabidopsis

Identifiers

PMID29784956
OpenAlexW2804344327

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.