Evidence map›Paper›PMID 29784904›Full record

ArticleScientific reports2018

Differential protein profiling as a potential multi-marker approach for obese patients with heart failure: A retrospective study.

Andrei Timotin, Mathieu Cinato, Frederic Boal, Sebastien Dejean, Rodica Anesia, Oleg Arnaut, Christine Lagente, Jerome Roncalli, Franck Desmoulin, Helene Tronchere and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Andrei TimotinINSERM U1048, University of Toulouse, Toulouse, Cedex 4, 31432, France.
Mathieu CinatoINSERM U1048, University of Toulouse, Toulouse, Cedex 4, 31432, France.
Frederic BoalINSERM U1048, University of Toulouse, Toulouse, Cedex 4, 31432, France.
Sebastien DejeanToulouse Mathematics Institute, University of Toulouse, Toulouse, Cedex 4, France.
Rodica AnesiaINSERM U1048, University of Toulouse, Toulouse, Cedex 4, 31432, France.
Oleg ArnautINSERM U1048, University of Toulouse, Toulouse, Cedex 4, 31432, France.
Christine LagenteDepartment of Cardiology, Toulouse University Hospital, Toulouse, Cedex 9, France.
Jerome RoncalliINSERM U1048, University of Toulouse, Toulouse, Cedex 4, 31432, France.
Franck DesmoulinToulouse NeuroImaging Center, ToNIC, University of Toulouse, Inserm U1214, Toulouse, Cedex 3, France.
Helene TronchereINSERM U1048, University of Toulouse, Toulouse, Cedex 4, 31432, France.
Oksana KunduzovaINSERM U1048, University of Toulouse, Toulouse, Cedex 4, 31432, France. Oxana.Koundouzova@inserm.fr.
Centre de Recherche en Cancérologie de Toulouse · FRInstitut des Maladies Métaboliques et Cardiovasculaires · FRUniversité Fédérale de Toulouse Midi-Pyrénées · FRCentre Hospitalier Universitaire de Toulouse · FRInserm · FRInstitut National des Sciences Appliquées de Toulouse · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Identification of novel circulating biomarkers predicting death and major cardio-metabolic events in obese patients with heart failure (HF) remains a research priority. In this study, we compared multi-marker profile of non-obese (NOB) and obese (OB) HF patients in relation to mortality outcome. The new multiplex proximity extension assay technology was used to analyze the levels of 92 proteins in plasma samples from HF patients according to body mass index (BMI) categories. At 2-year follow-up, all-cause mortality rates were significantly greater in NOB patients (BMI < 30 kg/m

Indexed as

AgedBiomarkersHeart FailureHumansMaleMiddle AgedObesityProteomeRetrospective StudiesBiomarkersProteome

Identifiers

PMID29784904
PMCPMC5962559
OpenAlexW2803315106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.