Evidence map›Paper›PMID 29784886›Full record

ArticleJournal of bacteriology2018

Legionella pneumophila Is Directly Sensitive to 2-Deoxyglucose-Phosphate via Its UhpC Transporter but Is Indifferent to Shifts in Host Cell Glycolytic Metabolism.

Jordan V Price, Kallie Jiang, Abigail Galantowicz, Alana Freifeld, Russell E Vance

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Interfering with Autophagy: The Opposing Strategies Deployed byFrontiers in cellular and infection microbiology · 2020
    Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jordan V PriceDepartment of Biology, Oberlin College, Oberlin, Ohio, USA jprice@oberlin.edu.
Kallie JiangDepartment of Biology, Oberlin College, Oberlin, Ohio, USA.
Abigail GalantowiczDepartment of Biology, Oberlin College, Oberlin, Ohio, USA.
Alana FreifeldDivision of Immunology and Pathogenesis, Department of Molecular and Cell Biology, and Cancer Research Laboratory, University of California, Berkeley, California, USA.
Russell E VanceDivision of Immunology and Pathogenesis, Department of Molecular and Cell Biology, and Cancer Research Laboratory, University of California, Berkeley, California, USA.
Oberlin College · USUniversity of California, Berkeley · US

Funding

The role of Listeria cyclic-di-AMP during infection and immunityP01AI063302 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI STANLEY, SARAH A · 2004 to 2025
$45.5M
Functional and Structural Dissection of Inflammasome ActivationR37AI075039 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI RUSSELL E VANCE · 2018 to 2026
$3.8M
Specificity and in vivo function of the Naip/Nlrc4 inflammasomesR01AI075039 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI VANCE, RUSSELL E · 2008 to 2017
$3.6M
Howard Hughes Medical InstituteNIAID NIH HHS P01 AI063302NIAID NIH HHS R01 AI075039NIAID NIH HHS R37 AI075039
6 · The paper itself

Abstract

Toll-like receptor (TLR) stimulation induces a pronounced shift to increased glycolytic metabolism in mammalian macrophages. We observed that bone marrow-derived macrophages (BMMs) increase glycolysis in response to infection with

Indexed as

AnimalsBacterial ProteinsGlucoseGlucosephosphatesGlycolysisHost Microbial InteractionsLegionella pneumophilaMacrophagesMembrane Transport ProteinsMiceMice, Inbred C57BLMutationBacterial ProteinsGlucoseGlucosephosphatesMembrane Transport ProteinsuhpC protein, bacteria2-deoxyglucoseLegionella pneumophilamacrophagesmetabolism

Identifiers

PMID29784886
PMCPMC6060365
OpenAlexW2804032159

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.