Evidence map›Paper›PMID 29784885›Full record

ArticleJournal of bacteriology2018

Pseudomonas aeruginosa Regulated Intramembrane Proteolysis: Protease MucP Can Overcome Mutations in the AlgO Periplasmic Protease To Restore Alginate Production in Nonmucoid Revertants.

Camila Delgado, Laura Florez, Ivonne Lollett, Christine Lopez, Shiva Kangeyan, Hansi Kumari, Marios Stylianou, Robert J Smiddy, Lisa Schneper, Robert T Sautter and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Journal of bacteriology · 2024
    Article
  2. Lytic transglycosylase Slt of Pseudomonas aeruginosa as a periplasmic hub protein.Protein science : a publication of the Protein Society · 2024
    Article
  3. Frontiers in cellular and infection microbiology · 2024
    Article
  4. Article
  5. Review
  6. BosR: A novel biofilm-specific regulator inFrontiers in microbiology · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Camila Delgado *Department of Human and Molecular Genetics, Herbert Wertheim College of Medicine, Biomolecular Sciences Institute, Florida International University, Miami, Florida, USA.
Laura Florez *Department of Human and Molecular Genetics, Herbert Wertheim College of Medicine, Biomolecular Sciences Institute, Florida International University, Miami, Florida, USA.
Ivonne LollettDepartment of Biological Sciences, Florida International University, Miami, Florida, USA.
Christine LopezBurnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida, USA.
Shiva KangeyanArchimedean Academy, Miami, Florida, USA.
Hansi KumariDepartment of Human and Molecular Genetics, Herbert Wertheim College of Medicine, Biomolecular Sciences Institute, Florida International University, Miami, Florida, USA.
Marios StylianouDepartment of Clinical Microbiology, University of Umeå, Umeå, Sweden.
Robert J SmiddyDepartment of Human and Molecular Genetics, Herbert Wertheim College of Medicine, Biomolecular Sciences Institute, Florida International University, Miami, Florida, USA.
Lisa SchneperDepartment of Human and Molecular Genetics, Herbert Wertheim College of Medicine, Biomolecular Sciences Institute, Florida International University, Miami, Florida, USA.
Robert T SautterDepartment of Biological Sciences, Florida International University, Miami, Florida, USA.
David SmithSt. Thomas Aquinas High School, Fort Lauderdale, Florida, USA.
George SzatmariDépartement de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, QC, Canada george.szatmari@umontreal.ca.
Kalai MatheeDepartment of Human and Molecular Genetics, Herbert Wertheim College of Medicine, Biomolecular Sciences Institute, Florida International University, Miami, Florida, USA.
Florida International University · USSt. Thomas Aquinas College · USUmeå University · SEUniversité de Montréal · CAUniversity of Central Florida · US

Funding

MBRS RESEARCH INITIATIVE FOR SCIENTIFIC ENHANCEMENTR25GM061347 · NIGMS · FLORIDA INTERNATIONAL UNIVERSITY · PI LICKLITER, ROBERT E · 2000 to 2016
$14.7M
Decoding P. aeruginosa RIP cascade and discovering its inhibitors as therapeuticsR15AI111210 · NIAID · FLORIDA INTERNATIONAL UNIVERSITY · PI MATHEE, KALAI · 2015 to 2015
$421k
NIAID NIH HHS R15 AI111210NIGMS NIH HHS R25 GM061347
6 · The paper itself

Abstract

The progression of cystic fibrosis (CF) from an acute to a chronic disease is often associated with the conversion of the opportunistic pathogen

Indexed as

ProteolysisAlginatesBacterial ProteinsCystic FibrosisGene Expression Regulation, BacterialMutationPeptide HydrolasesPeriplasmPhenotypePseudomonas aeruginosaQuality of LifeSigma FactorAlginatesAlgU protein, Pseudomonas aeruginosaBacterial ProteinsPeptide HydrolasesSigma FactorAlgT/Uanti-sigma factorcystic fibrosismucoid conversionPrc/AlgO/TspRseP/MucP/YaeLsigma-22sigma-Esigma factorsσ22σE

Identifiers

PMID29784885
PMCPMC6060363
OpenAlexW2803548740

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.