Evidence map›Paper›PMID 29784862›Full record

ArticleInfection and immunity2018

Antibodies to Intercellular Adhesion Molecule 1-Binding Plasmodium falciparum Erythrocyte Membrane Protein 1-DBLβ Are Biomarkers of Protective Immunity to Malaria in a Cohort of Young Children from Papua New Guinea.

Sofonias K Tessema, Digjaya Utama, Olga Chesnokov, Anthony N Hodder, Clara S Lin, G L Abby Harrison, Jakob S Jespersen, Bent Petersen, Livingstone Tavul, Peter Siba and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
10.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 56 citations in OpenAlex.

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  10. Recombinant DBL2β-PfEMP1 of the IndonesianJournal of Taibah University Medical Sciences · 2021
    Article
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  16. Structural insights into diverse modes of ICAM-1 binding byProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 7 countries.

Sofonias K TessemaThe Walter and Eliza Hall Institute of Medical Research, Victoria, Australia.
Digjaya UtamaThe Walter and Eliza Hall Institute of Medical Research, Victoria, Australia.
Olga ChesnokovCharles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida, USA.
Anthony N HodderThe Walter and Eliza Hall Institute of Medical Research, Victoria, Australia.
Clara S LinThe Walter and Eliza Hall Institute of Medical Research, Victoria, Australia.
G L Abby HarrisonThe Walter and Eliza Hall Institute of Medical Research, Victoria, Australia.
Jakob S JespersenCentre for Medical Parasitology, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
Bent PetersenCenter for Biological Sequence Analysis, Technical University of Denmark, Kgs. Lyngby, Denmark.
Livingstone TavulVector Borne Diseases Unit, Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea.
Peter SibaVector Borne Diseases Unit, Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea.
Dominic KwiatkowskiWellcome Trust Sanger Institute, Hinxton, United Kingdom.
Thomas LavstsenCentre for Medical Parasitology, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-3044-4249
Diana S HansenThe Walter and Eliza Hall Institute of Medical Research, Victoria, Australia.
Andrew V OleinikovCharles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida, USA.
Ivo MuellerThe Walter and Eliza Hall Institute of Medical Research, Victoria, Australia.
Alyssa E BarryThe Walter and Eliza Hall Institute of Medical Research, Victoria, Australia barry@wehi.edu.au.ORCID https://orcid.org/0000-0002-1189-2310
The University of Melbourne · AUFlorida Atlantic University · USPapua New Guinea Institute of Medical Research · PGUniversity of Copenhagen · DKAIMST University · MYInstitut Pasteur · FRWellcome Sanger Institute · GB

Funding

Identification of vaccine candidates against severe malariaR01AI092120 · NIAID · SEATTLE BIOMEDICAL RESEARCH INSTITUTE · PI OLEINIKOV, ANDREW V · 2011 to 2014
$1.6M
NIAID NIH HHS R01 AI092120Wellcome Trust 204911/Z/16/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antibodies, ProtozoanAntigens, ProtozoanBiomarkersChild, PreschoolEndothelial Protein C ReceptorFemaleFollow-Up StudiesGenetic VariationHumansIncidenceInfantIntercellular Adhesion Molecule-1Malaria, FalciparumMalePapua New GuineaPhylogenyAntibodies, ProtozoanAntigens, ProtozoanBiomarkersEndothelial Protein C Receptorerythrocyte membrane protein 1, Plasmodium falciparumIntercellular Adhesion Molecule-1PROCR protein, humanProtozoan ProteinsantibodiesDBLβdiversityEPCRICAM1malariaPapua New GuineaPfEMP1var genes

Identifiers

PMID29784862
PMCPMC6056858
OpenAlexW2803759292

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.