Evidence map›Paper›PMID 29784844›Full record

SynthesisAntimicrobial agents and chemotherapy2018

Incidences of Pseudomonas aeruginosa-Associated Ventilator-Associated Pneumonia within Studies of Respiratory Tract Applications of Polymyxin: Testing the Stoutenbeek Concurrency Postulates.

James C Hurley

Open access · bronzeAbstract readMeta-Analysis
In one paragraph

Synthesis in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Viruses · 2024
    Review
  3. Infectious medicine · 2023
    Review
  4. Selective digestive decontamination-Con.Intensive care medicine · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Unusually High Incidences ofOpen forum infectious diseases · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

James C HurleyDepartment of Rural Health, Melbourne Medical School, University of Melbourne, Melbourne, Australia hurleyjc@unimelb.edu.au.ORCID 0000-0002-5885-2084
The University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regimens containing topical polymyxin appear highly effective at preventing ventilator-associated pneumonia (VAP) overall and, more so, VAP caused by Gram-negative bacteria. However, Stoutenbeek's postulates that VAP incidences within studies of topical antibiotics depend on the context of whether the component (control and intervention) groups of each study were concurrent versus nonconcurrent remain untested. The literature was searched for concurrent control (CC) versus nonconcurrent control (NCC) designed studies of respiratory tract applications of topical polymyxin to mechanically ventilated (MV) patients that reported incidences of

Indexed as

Anti-Bacterial AgentsAntibiotic ProphylaxisBenchmarkingHumansObservational Studies as TopicPneumonia, Ventilator-AssociatedPolymyxinsPseudomonas aeruginosaPseudomonas InfectionsRespiratory SystemSystematic Reviews as TopicAnti-Bacterial AgentsPolymyxinsantibiotic prophylaxisintensive caremechanical ventilationpolymyxinPseudomonasselective digestive decontaminationstudy designventilator-associated pneumonia

Identifiers

PMID29784844
PMCPMC6105782
OpenAlexW2804619920

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.