Evidence map›Paper›PMID 29784772›Full record

ArticleMolecular and cellular biology2018

A Heterochromatin Domain Forms Gradually at a New Telomere and Is Dynamic at Stable Telomeres.

Jinyu Wang, Jessica R Eisenstatt, Julien Audry, Kristen Cornelius, Matthew Shaughnessy, Kathleen L Berkner, Kurt W Runge

Open access · hybridAbstract read
In one paragraph

Article in Molecular and cellular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jinyu Wang *Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio, USA.
Jessica R Eisenstatt *Departments of Immunology and Molecular Genetics, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Julien Audry *Departments of Immunology and Molecular Genetics, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA audryj@ccf.org rungek@ccf.org.
Kristen CorneliusDepartment of Molecular Genetics, The Ohio State University, Columbus, Ohio, USA.
Matthew ShaughnessyDepartments of Immunology and Molecular Genetics, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Kathleen L BerknerDepartments of Immunology and Molecular Genetics, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Kurt W RungeDepartment of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio, USA audryj@ccf.org rungek@ccf.org.
Cleveland Clinic · USThe Ohio State University · US

Funding

STRUCTURE/FUNCTION ANALYSIS OF THE GAMMA-CARBOXYLASER01HL055666 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI BERKNER, KATHLEEN LUCILE · 1997 to 2017
$5.4M
Vitamin K Oxidoreductase: Function and PhysiologyR01HL081093 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI BERKNER, KATHLEEN LUCILE · 2008 to 2017
$3.4M
REGULATION OF TELOMERE LENGTHR01GM050752 · NIGMS · CLEVELAND CLINIC LERNER COM-CWRU · PI RUNGE, KURT W · 1994 to 2012
$3.2M
Regulation of lifespanR01AG051601 · NIA · CLEVELAND CLINIC LERNER COM-CWRU · PI RUNGE, KURT W · 2016 to 2020
$1.6M
NHLBI NIH HHS R01 HL055666NHLBI NIH HHS R01 HL081093NIA NIH HHS R01 AG051601NIGMS NIH HHS R01 GM050752
6 · The paper itself

Abstract

Heterochromatin domains play important roles in chromosome biology, organismal development, and aging, including centromere function, mammalian female X chromosome inactivation, and senescence-associated heterochromatin foci. In the fission yeast

Indexed as

Base SequenceDNA Breaks, Double-StrandedDNA, FungalGene SilencingGenome, FungalHeterochromatinHistone CodeKineticsModels, BiologicalSchizosaccharomycesSchizosaccharomyces pombe ProteinsTelomeraseTelomereTelomere HomeostasisDNA, FungalHeterochromatinSchizosaccharomyces pombe ProteinsTelomeraseura4 protein, S pombechromosome healingheterochromatin spreadingSchizosaccharomyces pombetelomere formation

Identifiers

PMID29784772
PMCPMC6048312
OpenAlexW2950225446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.