Evidence map›Paper›PMID 29784760›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Formation of the Intrathymic Dendritic Cell Pool Requires CCL21-Mediated Recruitment of CCR7

Emilie J Cosway, Izumi Ohigashi, Karin Schauble, Sonia M Parnell, William E Jenkinson, Sanjiv Luther, Yousuke Takahama, Graham Anderson

Open access · hybridAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Thymic Dendritic Cells Revisited.Immunological reviews · 2025
    Review
  4. Article
  5. Review
  6. Assembling the thymus medulla: Development and function of epithelial cell heterogeneity.BioEssays : news and reviews in molecular, cellular and developmental biology · 2024
    Article
  7. Article
  8. EvaluatingFrontiers in immunology · 2024
    Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Thymus and autoimmunity.Seminars in immunopathology · 2021
    Review
  14. Article
  15. Regulation of the Migration of Distinct Dendritic Cell Subsets.Frontiers in cell and developmental biology · 2021
    Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Emilie J CoswayInstitute for Immunology and Immunotherapy, Medical School, University of Birmingham, Birmingham B15 2TT, United Kingdom.
Izumi OhigashiDivision of Experimental Immunology, Institute of Advanced Medical Sciences, University of Tokushima, Tokushima 770-8503, Japan; and.
Karin SchaubleDepartment of Biochemistry, Centre for Immunity and Infection Lausanne, University of Lausanne, 1066 Epalinges, Switzerland.
Sonia M ParnellInstitute for Immunology and Immunotherapy, Medical School, University of Birmingham, Birmingham B15 2TT, United Kingdom.ORCID 0000-0002-4430-9072
William E JenkinsonInstitute for Immunology and Immunotherapy, Medical School, University of Birmingham, Birmingham B15 2TT, United Kingdom.
Sanjiv LutherDepartment of Biochemistry, Centre for Immunity and Infection Lausanne, University of Lausanne, 1066 Epalinges, Switzerland.ORCID 0000-0002-8758-957X
Yousuke TakahamaDivision of Experimental Immunology, Institute of Advanced Medical Sciences, University of Tokushima, Tokushima 770-8503, Japan; and.
Graham AndersonInstitute for Immunology and Immunotherapy, Medical School, University of Birmingham, Birmingham B15 2TT, United Kingdom; g.anderson@bham.ac.uk.ORCID 0000-0002-2917-4085
University of Birmingham · GBTokushima University · JPUniversity of Lausanne · CH

Funding

Thymus biologyZIABC011806 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI TAKAHAMA, YOUSUKE · 2018 to 2025
$13.5M
Arthritis Research UKBiotechnology and Biological Sciences Research CouncilMedical Research Council MR/N000919/1
6 · The paper itself

Abstract

During αβ T cell development in the thymus, migration of newly selected CD4

Indexed as

AnimalsCell MovementChemokine CCL21Dendritic CellsImmune ToleranceMiceMice, Inbred C57BLReceptors, CCR7ThymocytesThymus GlandCcr7 protein, mouseChemokine CCL21Receptors, CCR7

Identifiers

PMID29784760
PMCPMC6036229
OpenAlexW2803961873

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.