Evidence map›Paper›PMID 29784276›Full record

ArticleWomen's health issues : official publication of the Jacobs Institute of Women's Health

Associations of Drug Use, Violence, and Depressive Symptoms with Sexual Risk Behaviors Among Women with Alcohol Misuse.

Kristen Lee, Heidi E Hutton, Catherine R Lesko, Anne K Monroe, Anika Alvanzo, Mary E McCaul, Geetanjali Chander

Open access · greenAbstract read
In one paragraph

Article in Women's health issues : official publication of the Jacobs Institute of Women's Health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
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  3. Journal of CME · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kristen LeeDepartment of Medicine, Johns Hopkins University, Baltimore, Maryland.
Heidi E HuttonDepartment of Psychology, Johns Hopkins University, Baltimore, Maryland.
Catherine R LeskoDepartment of Epidemiology, Johns Hopkins University, Baltimore, Maryland.
Anne K MonroeDepartment of Medicine, Johns Hopkins University, Baltimore, Maryland.
Anika AlvanzoDepartment of Medicine, Johns Hopkins University, Baltimore, Maryland.
Mary E McCaulDepartment of Psychology, Johns Hopkins University, Baltimore, Maryland.
Geetanjali ChanderDepartment of Medicine, Johns Hopkins University, Baltimore, Maryland. Electronic address: Gchande1@jhmi.edu.
Johns Hopkins University · USJohns Hopkins Medicine · US

Funding

3/4 Alcohol Research Consortium in HIV - Epidemiological Research Arm (ARCH-ERA)U01AA020793 · NIAAA · UNIVERSITY OF WASHINGTON · PI CRANE, HEIDI M., LAU, BRYAN · 2011 to 2020
$5.8M
1/4 Alcohol Research Consortium in HIV-Administrative Core (ARCH-AC)U24AA020801 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI CHANDER, GEETANJALI, MCCAUL, MARY E · 2011 to 2021
$3.5M
Computerized BI for Binge Drinking HIV At-Risk & Infected African-American WomenR01AA018632 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI CHANDER, GEETANJALI · 2009 to 2013
$2.1M
The PERMSS Project-Promoting Education and Research on Mood, Stress, & SubstancesK23AA020316 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI ALVANZO, ANIKA A.H. · 2012 to 2016
$910k
Leveraging Patient-Reported Outcomes to Improve Retention in HIV CareK23MH105284 · NIMH · JOHNS HOPKINS UNIVERSITY · PI MONROE, ANNE KRESS · 2014 to 2016
$525k
NIAAA NIH HHS K23 AA020316NIAAA NIH HHS R01 AA018632NIAAA NIH HHS U01 AA020793NIAAA NIH HHS U24 AA020801NIMH NIH HHS K23 MH105284
6 · The paper itself

Abstract

backgroundAlcohol misuse is associated with increased human immunodeficiency virus sexual risk behaviors by women. Drug use, intimate partner violence (IPV), and depressive symptoms frequently co-occur, are well-recognized alcohol misuse comorbidities, and may interact to increase risk behaviors. Using a syndemic framework we examined associations between drug use, IPV, and depressive symptoms and sexual risk behaviors by 400 women with alcohol misuse attending an urban sexually transmitted infections clinic.

methodsParticipants completed computer-assisted interviews querying drug use, IPV, and depressive symptoms and sexual risk behavior outcomes-unprotected sex under the influence of alcohol, sex for drugs/money, and number of lifetime sexual partners. We used multivariable analysis to estimate prevalence ratios (PR) for independent and joint associations between drug use, IPV, and depressive symptoms and our outcomes. To investigate synergy between risk factors we calculated the relative excess prevalence owing to interaction for all variable combinations.

resultsIn multivariable analysis, drug use, IPV, and depressive symptoms alone and in combination were associated with higher prevalence/count of risk behaviors compared with women with alcohol misuse alone. The greatest prevalence/count occurred when all three were present (unprotected sex under the influence of alcohol [PR, 2.6; 95% confidence interval, 1.3-4.9]), sex for money or drugs [PR, 2.6; 95% confidence interval, 1.7-4.2], and number of lifetime partners [PR, 3.2; 95% confidence interval, 1.9-5.2]). Drug use, IPV, and depressive symptoms did not interact synergistically to increase sexual risk behavior prevalence.

conclusionsA higher prevalence of sexual risk behaviors by women with alcohol misuse combined with drug use, IPV, and depressive symptoms supports the need for alcohol interventions addressing these additional comorbidities.

Indexed as

AdultComorbidityCross-Sectional StudiesDepressionFemaleHIV InfectionsHumansIntimate Partner ViolenceMiddle AgedPrevalenceRisk-TakingSexual BehaviorSubstance-Related DisordersUnsafe SexYoung Adult

Identifiers

PMID29784276
PMCPMC6592607
OpenAlexW2804107708

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.