Evidence map›Paper›PMID 29784128›Full record

ArticleCellular immunology2019

Immunosurveillance of cancer and the heat shock protein-CD91 pathway.

Robert J Binder

Open access · greenAbstract read
In one paragraph

Article in Cellular immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  5. 7-nm MnTheranostics · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Robert J BinderDepartment of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, United States. Electronic address: rjb42@pitt.edu.
University of Pittsburgh · US

Funding

Heat shock protein gp96 and Treg responsesR21AI132875 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BINDER, ROBERT J · 2018 to 2019
$392k
NIAID NIH HHS R21 AI132875
6 · The paper itself

Abstract

The intracellular functions of heat shock proteins (HSPs) as chaperones of macromolecules are well known. Current observations point to a role of these chaperones in initiating and modulating immune responses to tumors via receptor(s) on dendritic cells. In this article we provide an insight into, and a basis for, the importance of these HSP-mediated immune responses in rejecting nascent and emerging tumors.

Indexed as

AnimalsDendritic CellsHeat-Shock ProteinsHumansLow Density Lipoprotein Receptor-Related Protein-1NeoplasmsHeat-Shock ProteinsLow Density Lipoprotein Receptor-Related Protein-1ChaperoneDendritic cellT regsTumor immunity

Identifiers

PMID29784128
PMCPMC6239979
OpenAlexW2804524927

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.