ArticleBMC endocrine disorders2018
Association between thyroid hormones and the components of metabolic syndrome.
Article in BMC endocrine disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 51 citations in OpenAlex.
- Navigating thyroid hormone signaling in liver fibrosis: mechanisms and clinical implications.Journal of endocrinological investigation · 2026Review
- Development and validation of a nomogram prediction model for thyroid dysfunction in patients with type 2 diabetes mellitus.Scientific reports · 2026Article
- Examining the association between thyroid dysfunction and metabolic syndrome components in a setting of high atherosclerotic heart disease risk factor prevalence: A cross-sectional study from Kochi, Kerala.Journal of family medicine and primary care · 2026Article
- Evaluating the association between TSH and FT4 levels and the incidence of metabolic syndrome: insights from the Tehran thyroid study using joint modeling.Scientific reports · 2025Article
- Clinical Patterns of Dyslipidemia in Patients With Initial-Treatment and Drug-Naïve Schizophrenia.Alpha psychiatry · 2025Article
- Impact of Early Life Famine Exposure on Body Composition and Metabolic Profiles in Adulthood.Maternal & child nutrition · 2025Article
- Association of estimated glucose disposal rate with incident cardiovascular disease under different metabolic and circadian rhythm states: findings from a national population-based prospective cohort study.Diabetology & metabolic syndrome · 2024Article
- The prevalence and determinants of diabetes mellitus and thyroid disorder comorbidity in Tabari cohort population.Scientific reports · 2024Article
- Thyroid Hormones and Diabetes in Euthyroid Hispanic/Latino Adults of Diverse Backgrounds: HCHS/SOL.Journal of the Endocrine Society · 2024Article
- Elevated thyroid autoantibodies as risk factors for metabolic dysfunction-associated fatty liver disease in type 2 diabetes mellitus.Frontiers in endocrinology · 2024Article
- Status of lipid control in Bangladeshi subjects with type 2 diabetes mellitus on lipid-lowering drugs: a multicenter, facility-based, cross-sectional study.BMC endocrine disorders · 2023Article
- Prevalence of dyslipidemia and the association with levels of TSH and T4 hormones among patients in south region of Jordan.Journal of medical biochemistry · 2023Article
- Sensitivity to thyroid hormone and risk of components of metabolic syndrome in a Chinese euthyroid population.Journal of diabetes · 2023Article
- Review
- Adolescence exposure to China's great famine period and the association of metabolic syndrome in adulthood: a retrospective study.BMC public health · 2022Article
- Association of free thyroxine with obstructive lung pattern in euthyroid middle-aged subjects: A population-based study.PloS one · 2022Article
- Analysis of epidemiological association patterns of serum thyrotropin by combining random forests and Bayesian networks.PloS one · 2022Article
- Lower normal free thyroxine is associated with a higher risk of metabolic syndrome: a retrospective cohort on Chinese population.BMC endocrine disorders · 2021Article
- The thyroid hormone levels and glucose and lipid metabolism in children with type 1 diabetes: a correlation analysis.Translational pediatrics · 2021Article
- Association between TSH Values and GFR Levels in Euthyroid Cases with Metabolic Syndrome.International journal of endocrinology · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThyroid hormones are known to have direct and indirect effects on metabolism. Individuals with metabolic syndrome, a disease that is growing in incidence at a rapid rate, are at higher risk for cardiovascular disease, diabetes, and cancer. The aim of this study was to identify whether significant correlations exist between thyroid hormone levels and components of the metabolic syndrome in the general population of Korea.
methodsThe data were collected from the sixth Korea National Health and Nutrition Examination Surveys from 2013 to 2015. A total of 1423 participants were tested for thyroid function. The analysis of variance and multiple linear regression were performed to analyze the relationship between thyroid hormone level and components of the metabolic syndrome.
resultsA positive association between free thyroxine and fasting glucose level was observed in patients with high free thyroxine levels (≥1.70 ng/dL, β = 15.992, p = < 0.0001), when compared with patients with normal-middle free thyroxine levels. Moreover, a negative association was observed between free thyroxine and triglyceride levels in patients with normal-high free thyroxine levels (β = - 21.145, p = 0.0054) and those with high free thyroxine levels (β = - 49.713, p = 0.0404).
conclusionFree thyroxine shows a partially positive association with fasting glucose and a partially negative association with triglycerides in the Korean population. In patients with abnormal thyroid function, follow up tests for glucose levels and lipid profiling during treatment for thyroid dysfunction would be beneficial in terms of overlooking metabolic syndrome and to prevent related diseases.
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