Evidence map›Paper›PMID 29783774›Full record

ArticleMolecules (Basel, Switzerland)2018

d-Amino Acid Peptide Residualizing Agents for Protein Radioiodination: Effect of Aspartate for Glutamate Substitution.

Marek Pruszynski, Choong Mo Kang, Eftychia Koumarianou, Ganesan Vaidyanathan, Michael R Zalutsky

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 4 countries.

Marek PruszynskiDepartment of Radiology, Duke University Medical Center, Durham, NC 27710, USA. m.pruszynski@ichtj.waw.pl.ORCID 0000-0001-8835-2462
Choong Mo KangDepartment of Radiology, Duke University Medical Center, Durham, NC 27710, USA. kcm1580@naver.com.
Eftychia KoumarianouDepartment of Radiology, Duke University Medical Center, Durham, NC 27710, USA. eftychia.koumarianou@duke-nus.edu.sg.
Ganesan VaidyanathanDepartment of Radiology, Duke University Medical Center, Durham, NC 27710, USA. ganesan.v@duke.edu.
Michael R ZalutskyDepartment of Radiology, Duke University Medical Center, Durham, NC 27710, USA. zalut001@mc.duke.edu.
Duke Medical Center · USInstytut Chemii i Techniki Jądrowej · PLKorea Institute of Radiological and Medical Sciences · KRNational University of Singapore · SG

Funding

RADIOTHERAPY USING MONOCLONAL ANTIBODIES AND ASTATINER01CA042324 · NCI · DUKE UNIVERSITY · PI ZALUTSKY, MICHAEL ROD · 1985 to 2020
$4.6M
ASTATINE AND IODINE RADIOLABELED MONOCLONAL ANTIBODIESR37CA042324 · NCI · DUKE UNIVERSITY · PI ZALUTSKY, MICHAEL ROD · 1999 to 2008
$3.8M
NCI NIH HHS R01 CA042324NCI NIH HHS R37 CA042324
6 · The paper itself

Abstract

The residualizing prosthetic agent

Indexed as

Amino Acid SubstitutionAnimalsAntibodies, MonoclonalAspartic AcidCell Line, TumorFemaleGlutamic AcidHumansIodine RadioisotopesKidneyMiceMolecular WeightOligopeptidesRadiopharmaceuticalsTissue DistributionXenograft Model Antitumor AssaysAntibodies, MonoclonalAspartic AcidGlutamic AcidIodine RadioisotopesN(epsilon)-(3-iodobenzoyl)-Lys(5)-Nalpha-maleimido-Gly(1)-glycyl-glutamyl-glutamyl-gluamyl-lysineOligopeptidesRadiopharmaceuticalsbreast cancerHER2radioiodinationresidualizing labelVHH

Identifiers

PMID29783774
PMCPMC6099567
OpenAlexW2803834972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.