ArticleSensors (Basel, Switzerland)2018
Grating-Coupled Surface Plasmon Resonance (GC-SPR) Optimization for Phase-Interrogation Biosensing in a Microfluidic Chamber.
Article in Sensors (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- SPR Sensing: From Biomolecular Interactions to Cell-Based Analysis.Biosensors · 2026Review
- Double-Sided Illumination Grating-Coupled Surface Plasmon Resonance Sensors Using Direct Optical Discs.Materials (Basel, Switzerland) · 2026Article
- A Plasmonic Nanoledge Array Sensor for Selective Detection of Cardiovascular Disease Biomarkers in Human Whole Blood.ACS applied nano materials · 2024Article
- Grating Structures for Silver-Based Surface Plasmon Resonance Sensors with Adjustable Excitation Angle.Sensors (Basel, Switzerland) · 2024Article
- An Improved Seeker Optimization Algorithm for Phase Sensitivity Enhancement of a Franckeite- and WSMicromachines · 2024Article
- Differential Evolution Particle Swarm Optimization for Phase-Sensitivity Enhancement of Surface Plasmon Resonance Gas Sensor Based on MXene and Blue Phosphorene/Transition Metal Dichalcogenide Hybrid Structure.Sensors (Basel, Switzerland) · 2023Article
- Optimizing Stability and Performance of Silver-Based Grating Structures for Surface Plasmon Resonance Sensors.Sensors (Basel, Switzerland) · 2023Article
- The Design of a Glycerol Concentration Sensor Based on an LRSPP Hybrid Photonic Biosensor.Sensors (Basel, Switzerland) · 2023Article
- A Self-Referenced Refractive Index Sensor Based on Gold Nanoislands.Sensors (Basel, Switzerland) · 2022Article
- IP-Dip-Based SPR Structure for Refractive Index Sensing of Liquid Analytes.Nanomaterials (Basel, Switzerland) · 2021Article
- Multi-Color Enhanced Fluorescence Imaging of a Breast Cancer Cell with A Hole-Arrayed Plasmonic Chip.Micromachines · 2020Article
- Development of Graphene Quantum Dots-Based Optical Sensor for Toxic Metal Ion Detection.Sensors (Basel, Switzerland) · 2019Review
- Metadevices with Potential Practical Applications.Molecules (Basel, Switzerland) · 2019Review
- The Sensitivity of Grating-Based SPR Sensors with Wavelength Interrogation.Sensors (Basel, Switzerland) · 2019Article
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Surface Plasmon Resonance (SPR)-based sensors have the advantage of being label-free, enzyme-free and real-time. However, their spreading in multidisciplinary research is still mostly limited to prism-coupled devices. Plasmonic gratings, combined with a simple and cost-effective instrumentation, have been poorly developed compared to prism-coupled system mainly due to their lower sensitivity. Here we describe the optimization and signal enhancement of a sensing platform based on phase-interrogation method, which entails the exploitation of a nanostructured sensor. This technique is particularly suitable for integration of the plasmonic sensor in a lab-on-a-chip platform and can be used in a microfluidic chamber to ease the sensing procedures and limit the injected volume. The careful optimization of most suitable experimental parameters by numerical simulations leads to a 30⁻50% enhancement of SPR response, opening new possibilities for applications in the biomedical research field while maintaining the ease and versatility of the configuration.
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