Evidence map›Paper›PMID 29783680›Full record

ReviewInternational journal of molecular sciences2018

Rafaela da Trindade, Joyce Kelly da Silva, William N Setzer

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05308732 (Phase I Study of Multiple Ascending Dose, to Investigate the Safety and Tolerability of the Use of Copaiba in Patients With Oral Cancer Submitted to Radiotherapy), which is not on this map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05308732 phase1active not recruitingnot on this mapstarted 2021, after this paper: background citation

Phase I Study of Multiple Ascending Dose, to Investigate the Safety and Tolerability of the Use of Copaiba in Patients With Oral Cancer Submitted to Radiotherapy

TypeinterventionalSponsorInstituto Nacional de Cancer, BrazilRan2021 to 2026Enrolled20ConditionsHead and Neck Neoplasms, Mucositis Oral, Radiotherapy, ComplicationsArmsCopaiba
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 137 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Genomic Diversity and Structure ofPlants (Basel, Switzerland) · 2025
    Article
  11. Pathogens (Basel, Switzerland) · 2025
    Article
  12. Bioavailability for the Improved Therapeutic Profile ofInternational journal of molecular sciences · 2025
    Article
  13. Article
  14. Review
  15. Review
  16. Skin Tear Treatment withPharmaceuticals (Basel, Switzerland) · 2024
    Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Rafaela da TrindadePrograma de Pós-Graduação em Biotecnologia, Universidade Federal do Pará, 66075-900 Belém, Brazil. rcabral@ufpa.br.
Joyce Kelly da SilvaPrograma de Pós-Graduação em Biotecnologia, Universidade Federal do Pará, 66075-900 Belém, Brazil. joycekellys@ufpa.br.ORCID 0000-0002-9351-876X
William N SetzerDepartment of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA. wsetzer@chemistry.uah.edu.ORCID 0000-0002-3639-0528
Universidade Federal do Pará · BRAromatic Plant Research Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oleoresin of

Indexed as

Anti-Inflammatory AgentsEnzyme InhibitorsFabaceaeMolecular Docking SimulationOils, VolatilePlant ExtractsAnti-Inflammatory AgentsEnzyme InhibitorsOils, VolatileoleoresinsPlant Extractsbiological activitycopaibaditerpenoidsessential oilmolecular targetsoleoresinsesquiterpenoids

Identifiers

PMID29783680
PMCPMC5983702
OpenAlexW2803295501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.