ArticleEnvironmental research2018
Indoor black carbon and biomarkers of systemic inflammation and endothelial activation in COPD patients.
Article in Environmental research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Biomarkers of the relationship of particulate matter exposure with the progression of chronic respiratory diseases.The Korean journal of internal medicine · 2024Pooled it
- Effects of Fine Particulate Matter on Systemic Inflammatory Biomarkers in Elderly Patients with Chronic Obstructive Pulmonary Disease Versus the Healthy Elderly: A Pilot Study.International journal of molecular sciences · 2026Article
- Associations of daily air temperature with lung function and biomarkers of inflammation and oxidative stress in chronic obstructive pulmonary disease.Annals of the American Thoracic Society · 2026Article
- Angiotensin-Converting Enzyme (ACE) Inhibitors and Statins Mitigate Negative Cardiovascular and Pulmonary Effects of Particulate Matter in a Mouse Exposure Model.Antioxidants (Basel, Switzerland) · 2026Article
- Association of PM2.5 exposure with 10-year atherosclerotic cardiovascular disease risk: a mediation analysis of blood and urinary biomarkers.Frontiers in public health · 2026Article
- Modifying effect of statin use on the association between nitrogen dioxide exposure and ischemic heart disease in patients with hypertension.Clinical hypertension · 2026Article
- Residential radon decay products are associated with cough and phlegm in patients with COPD.Ecotoxicology and environmental safety · 2024Article
- Elevated Exposure to Air Pollutants Accelerates Primary Glomerular Disease Progression.Kidney international reports · 2024Article
- Indoor and ambient black carbon and fine particulate matter associations with blood biomarkers in COPD patients.The Science of the total environment · 2024Article
- Indoor (residential) and ambient particulate matter associations with urinary oxidative stress biomarkers in a COPD cohort.The Science of the total environment · 2023Article
- Pulmonary, inflammatory, and oxidative effects of indoor nitrogen dioxide in patients with COPD.Environmental epidemiology (Philadelphia, Pa.) · 2023Article
- Biomarkers of particulate matter exposure in patients with chronic obstructive pulmonary disease: a systematic review.Journal of thoracic disease · 2023Review
- Adverse Effects of Prenatal Exposure to Oxidized Black Carbon Particles on the Reproductive System of Male Mice.Toxics · 2023Article
- Determinants of indoor carbonaceous aerosols in homes in the Northeast United States.Journal of exposure science & environmental epidemiology · 2023Article
- Intense solar activity reduces urinary 6-sulfatoxymelatonin in patients with COPD.Respiratory research · 2023Article
- Associations between Household Solid Fuel Use, Obesity, and Cardiometabolic Health in China: A Cohort Study from 2011 to 2018.International journal of environmental research and public health · 2023Article
- Particle radioactivity from radon decay products and reduced pulmonary function among chronic obstructive pulmonary disease patients.Environmental research · 2023Article
- Modification of associations between indoor particulate matter and systemic inflammation in individuals with COPD.Environmental research · 2022Article
- Tussilagone protects acute lung injury from PM2.5 via alleviating Hif-1α/NF-κB-mediated inflammatory response.Environmental toxicology · 2022Article
- Aspirin eugenol ester alleviates lipopolysaccharide-induced acute lung injury in rats while stabilizing serum metabolites levels.Frontiers in immunology · 2022Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
rationaleEvidence linking traffic-related particle exposure to systemic effects in chronic obstructive lung disease (COPD) patients is limited.
objectivesAssess relationships between indoor black carbon (BC), a tracer of traffic-related particles, and plasma biomarkers of systemic inflammation and endothelial activation.
methodsBC was measured by reflectance in fine particle samples over a mean of 7.6 days in homes of 85 COPD patients up to 4 times seasonally over a year. After the completion of sampling, plasma C-reactive protein (CRP), interleukin-6 (IL-6), and soluble vascular adhesion molecule-1 (sVCAM-1) were measured. Current smokers and homes with major sources of BC were excluded; therefore, indoor BC was primarily a measure of infiltrated outdoor BC. Mixed effects regression models with a random intercept for each participant were used to assess BC effects at different times (1-9 days before phlebotomy) and in the multi-day sample.
resultsMeasured median BC was 0.19 µg/m
conclusionsThese results demonstrate exposure-response relationships between indoor BC with biomarkers of systemic inflammation in COPD patients, with stronger relationships in persons not using statins and with diabetes.
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Registered trials
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