Evidence map›Paper›PMID 29782832›Full record

ArticleJournal of molecular biology2018

Nup159 Weakens Gle1 Binding to Dbp5 But Does Not Accelerate ADP Release.

Emily V Wong, Shawn Gray, Wenxiang Cao, Rachel Montpetit, Ben Montpetit, Enrique M De La Cruz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Structure, function and assembly of nuclear pore complexes.Nature reviews. Molecular cell biology · 2026
    Review
  2. Review
  3. Article
  4. Gle1 is required for tRNA to stimulate Dbp5 ATPase activitybioRxiv : the preprint server for biology · 2023
    Article
  5. Structure and Function of the Nuclear Pore Complex.Cold Spring Harbor perspectives in biology · 2022
    Review
  6. Article
  7. Review
  8. Force and phosphate release from Arp2/3 complex promote dissociation of actin filament branches.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  9. Article
  10. The Structure of the Nuclear Pore Complex (An Update).Annual review of biochemistry · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Emily V WongDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA.
Shawn GrayDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA.
Wenxiang CaoDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA.
Rachel MontpetitDepartment of Viticulture and Enology, University of California, Davis, Davis, CA 95616, USA; Department of Food Science and Technology, University of California, Davis, Davis, CA 95616, USA.
Ben MontpetitDepartment of Viticulture and Enology, University of California, Davis, Davis, CA 95616, USA; Department of Food Science and Technology, University of California, Davis, Davis, CA 95616, USA. Electronic address: benmontpetit@ucdavis.edu.
Enrique M De La CruzDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA. Electronic address: enrique.delacruz@yale.edu.
Yale University · USUniversity of California, Davis · US

Funding

Skill Development for Diverse Scientific Careers: A New Course Predoctoral Program in Cellular and Molecular BiologyT32GM007223 · NIGMS · YALE UNIVERSITY · PI BASERGA, SUSAN J · 1985 to 2019
$31.0M
Function and Regulation of a DEAD-box protein in mRNA ExportR01GM124120 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MONTPETIT, BENJAMEN H.W. · 2017 to 2021
$2.0M
NIGMS NIH HHS R01 GM124120NIGMS NIH HHS T32 GM007223
6 · The paper itself

Abstract

Dbp5, DDX19 in humans, is an essential DEAD-box protein involved in mRNA export, which has also been linked to other cellular processes, including rRNA export and translation. Dbp5 ATPase activity is regulated by several factors, including RNA, the nucleoporin proteins Nup159 and Gle1, and the endogenous small-molecule inositol hexakisphosphate (InsP

Indexed as

Adenosine DiphosphateAdenosine TriphosphateDEAD-box RNA HelicasesHumansMagnesiumNuclear Pore Complex ProteinsNucleocytoplasmic Transport Proteinsortho-AminobenzoatesProtein BindingRNA3'-O-(N-methylanthraniloyl)adenosine 5'-diphosphate3'-O-(N-methylanthraniloyl) ATPAdenosine DiphosphateAdenosine TriphosphateDDX19B protein, humanDEAD-box RNA HelicasesGle1 protein, humanMagnesiumNuclear Pore Complex ProteinsNucleocytoplasmic Transport Proteinsortho-AminobenzoatesRNADbp5DEAD-box proteinGle1kineticsNup159

Identifiers

PMID29782832
PMCPMC6003625
OpenAlexW2803416254

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.