Evidence map›Paper›PMID 29782154›Full record

ArticleJournal of the American Chemical Society2018

miCLIP-MaPseq, a Substrate Identification Approach for Radical SAM RNA Methylating Enzymes.

Vanja Stojković, Tongyue Chu, Gabriel Therizols, David E Weinberg, Danica Galonić Fujimori

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. CNature communications · 2024
    Article
  5. MePMe-seq: antibody-free simultaneous mNature communications · 2023
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vanja StojkovićDepartment of Cellular and Molecular Pharmacology , University of California , San Francisco , California 94158 , United States.
Tongyue ChuDepartment of Cellular and Molecular Pharmacology , University of California , San Francisco , California 94158 , United States.
Gabriel TherizolsDepartment of Cellular and Molecular Pharmacology , University of California , San Francisco , California 94158 , United States.
David E WeinbergDepartment of Cellular and Molecular Pharmacology , University of California , San Francisco , California 94158 , United States.
Danica Galonić FujimoriDepartment of Cellular and Molecular Pharmacology , University of California , San Francisco , California 94158 , United States.ORCID 0000-0002-4066-9417

Funding

Radical SAM-dependent methylation in antibiotic resistanceR01AI137270 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Danica Galonic Fujimori · 2018 to 2026
$3.8M
Formation and regulation of the translating mRNPDP5OD017895 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WEINBERG, DAVID ERIC · 2013 to 2017
$1.9M
Radical SAM MethytransferasesR01AI095393 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FUJIMORI, DANICA GALONIC · 2011 to 2015
$1.7M
NIAID NIH HHS R01 AI095393NIAID NIH HHS R01 AI137270NIH HHS DP5 OD017895
6 · The paper itself

Abstract

Although present across bacteria, the large family of radical SAM RNA methylating enzymes is largely uncharacterized. Escherichia coli RlmN, the founding member of the family, methylates an adenosine in 23S rRNA and several tRNAs to yield 2-methyladenosine (m

Indexed as

AdenosineCysteineEscherichia coliEscherichia coli ProteinsImmunoprecipitationMethylationMethyltransferasesMutationRNAS-AdenosylmethionineSequence Analysis, RNASubstrate SpecificityAdenosineCysteineEscherichia coli ProteinsMethyltransferasesRlmN protein, E coliRNAS-Adenosylmethionine

Identifiers

PMID29782154
PMCPMC7207077

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.