Evidence map›Paper›PMID 29782071›Full record

ArticleInternational forum of allergy & rhinology2018

Evaluation of idiopathic olfactory loss with chemosensory event-related potentials and magnetic resonance imaging.

Jia Liu, Jayant M Pinto, Ling Yang, Linyin Yao, Xutao Miao, Yongxiang Wei

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International forum of allergy & rhinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. The effect of nasopharyngeal obstruction on the olfactory bulb volume and olfactory sulcus depth in children : First author.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  3. Article
  4. Olfactory Evaluation in Clinical Medical Practice.Journal of clinical medicine · 2022
    Review
  5. [Analysis of clinical characteristics in the patient with olfactory disorders].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2022
    Article
  6. International consensus statement on allergy and rhinology: Olfaction.International forum of allergy & rhinology · 2022
    Review
  7. Article
  8. [Predictors of posttreatment olfactory improvement in patients with postviral olfactory dysfunction].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2021
    Article
  9. Prognostic value of olfactory evoked potentials in patients with post-infectious olfactory dysfunction.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Jia LiuDepartment of Otolaryngology-Head and Neck Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Jayant M PintoSection of Otolaryngology-Head and Neck Surgery, Department of Surgery, The University of Chicago, Chicago, IL.
Ling YangCentral Laboratory, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Linyin YaoDepartment of Otolaryngology-Head and Neck Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Xutao MiaoDepartment of Otorhinolaryngology, Beijing United Family Healthcare, Beijing, China.
Yongxiang WeiDepartment of Otolaryngology-Head and Neck Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Beijing Anzhen Hospital · CNCapital Medical University · CNBeijing United Family Hospital · CNUniversity of Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIdiopathic olfactory loss (IOL) accounts for a sizable fraction of olfactory dysfunction, but very little is known about its etiology and electrophysiological changes in the olfactory pathway.

methodsWe analyzed the physiology of IOL using chemosensory event-related potentials (ERPs) (olfactory and trigeminal: oERP and tERP) and olfactory pathway magnetic resonance imaging (MRI) measured in adult patients with IOL and healthy controls. Subjective olfactory function was measured by Toyota and Takagi (T&T) olfactometry and Sniffin' Sticks (SS).

resultsOlfactory function was worse in patients with IOL compared to controls (T&T, p < 0.001; SS, p < 0.001). oERPs could be evoked in 17 IOL patients. Signals in these patients showed lower amplitude in the N

conclusionIOL patients show neurophysiologic deficits and some anatomic differences compared to healthy controls.

Indexed as

Olfaction DisordersAdultEvoked PotentialsFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedOlfactory BulbOlfactory PathwaysSmellchemosensory event-related potentialsclinical featuresidiopathic olfactory lossMRIolfactory function

Identifiers

PMID29782071
PMCPMC6282607
OpenAlexW2803324840

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.