Evidence map›Paper›PMID 29781880›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2018

Willingness to Donate Organs Among People Living With HIV.

Anh Q Nguyen, Saad K Anjum, Samantha E Halpern, Komal Kumar, Sarah E Van Pilsum Rasmussen, Brianna Doby, Ashton A Shaffer, Allan B Massie, Aaron A R Tobian, Dorry L Segev and 2 more

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Review
  3. Organ donation and HIV: Awareness and willingness to be a living donor among people with HIV in Uganda.Transplant infectious disease : an official journal of the Transplantation Society · 2024
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  8. Efficacy of hope: Analysis of organ quality and availability among deceased HIV-positive donors.Transplant infectious disease : an official journal of the Transplantation Society · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Anh Q Nguyen
Saad K AnjumSurgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Samantha E HalpernSurgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Komal KumarSurgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Sarah E Van Pilsum RasmussenSurgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Brianna Doby
Ashton A ShafferSurgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Allan B MassieSurgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Aaron A R TobianDepartment of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD.
Dorry L SegevSurgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Jeremy SugarmanBerman Institute of Bioethics, Johns Hopkins University, Baltimore, MD.
Christine M Durand
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007309 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI COX, ANDREA L · 1985 to 2019
$43.2M
HOPE in Action: A Clinical Trial of HIV-to-HIV Liver TransplantationU01AI138897 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Christine Marie Durand, DORRY L. SEGEV · 2018 to 2026
$25.5M
HOPE in Action: A clinical trial of HIV-to-HIV deceased donor kidney transplantationU01AI134591 · NIAID · JOHNS HOPKINS UNIVERSITY · PI DURAND, CHRISTINE MARIE, SEGEV, DORRY L. · 2017 to 2021
$11.0M
Unlocking the Potential of HIV-Infected Deceased Donors for Organ TransplantationR01AI120938 · NIAID · JOHNS HOPKINS UNIVERSITY · PI TOBIAN, AARON A · 2016 to 2021
$4.3M
Patient Oriented Research in Kidney Disease and Transplant SurgeryK24DK101828 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SEGEV, DORRY L. · 2014 to 2018
$922k
Optimal Antiretroviral Therapy During Bone Marrow Transplant in HIV-1 InfectionK23CA177321 · NCI · JOHNS HOPKINS UNIVERSITY · PI DURAND, CHRISTINE MARIE · 2014 to 2018
$808k
HOPE in Action: HIV-to-HIV Solid Organ Transplantation in the USR34AI123023 · NIAID · JOHNS HOPKINS UNIVERSITY · PI DURAND, CHRISTINE MARIE · 2016 to 2016
$243k
Understanding the Impact of HIV on Survival in End-Stage Liver DiseaseF30DK116658 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SHAFFER, ASHTON A · 2017 to 2019
$149k
NCI NIH HHS K23 CA177321NIAID NIH HHS P30 AI094189NIAID NIH HHS R01 AI120938NIAID NIH HHS R34 AI123023NIAID NIH HHS U01 AI134591NIAID NIH HHS U01 AI138897NIDDK NIH HHS F30 DK116658NIDDK NIH HHS K24 DK101828NIGMS NIH HHS T32 GM007309
6 · The paper itself

Abstract

backgroundWith passage of the HIV Organ Policy Equity (HOPE) Act, people living with HIV (PLWH) can donate organs to PLWH awaiting transplant. Understanding knowledge and attitudes regarding organ donation among PLWH in the United States is critical to implementing the HOPE Act.

methodsPLWH were surveyed regarding their knowledge, attitudes, and beliefs about organ donation and transplantation at an urban academic HIV clinic in Baltimore, MD, between August 2016 and October 2016. Responses were compared using Fisher exact and χ tests.

resultsAmong 114 survey respondents, median age was 55 years, 47.8% were female, and 91.2% were African American. Most were willing to be deceased donors (79.8%) or living donors (62.3%). Most (80.7%) were aware of the US organ shortage; however, only 24.6% knew about the HOPE Act, and only 21.1% were registered donors. Respondents who trusted the medical system or thought their organs would function adequately in recipients were more likely to be willing to be deceased donors (P < 0.001). Respondents who were concerned about surgery, worse health postdonation, or need for changes in HIV treatment because of donation were less likely to be willing to be living donors (P < 0.05 for all). Most believed that PLWH should be permitted to donate (90.4%) and that using HIV+ donor organs for transplant would reduce discrimination against PLWH (72.8%).

conclusionsMany of the PLWH surveyed expressed willingness to be organ donors. However, knowledge about the HOPE Act and donor registration was low, highlighting a need to increase outreach.

Indexed as

Health Knowledge, Attitudes, PracticeAdolescentAdultChildFemaleHIV InfectionsHumansLiving DonorsMaleMiddle AgedTissue DonorsYoung Adult

Identifiers

PMID29781880
PMCPMC6092203
OpenAlexW2803646107

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.