ArticleAfrican journal of primary health care & family medicine2018
The management of diabetic ketoacidosis at a rural regional hospital in KwaZulu-Natal.
Article in African journal of primary health care & family medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- A systematic literature review on the burden of diabetic ketoacidosis in type 2 diabetes mellitus.Diabetes, obesity & metabolism · 2025Pooled it
- Mapping the storm: a scoping review of diabetic emergencies in Africa.Frontiers in clinical diabetes and healthcare · 2026Review
- Precipitating factors and clinical outcomes of diabetic ketoacidosis in Eastern Cape, South Africa.Journal of the colleges of medicine of South Africa · 2025Article
- The dawdle, dally and delay of diabetic ketoacidosis: Decoding the emergency department length of stay - A chart review.Journal of the colleges of medicine of South Africa · 2025Article
- Article
- Clinical presentation and outcomes of care in adults with diabetic ketoacidosis pre-COVID-19 and during-COVID-19 at a tertiary, referral hospital in Nairobi, Kenya.BMC endocrine disorders · 2024Article
- Incidence and determinants of diabetic ketoacidosis among people with diabetes in Woldiya comprehensive specialized hospital, Ethiopia: a retrospective cohort study.BMC endocrine disorders · 2024Article
- Comprehensive review of diabetic ketoacidosis: an update.Annals of medicine and surgery (2012) · 2023Article
- The phenotype of type 1 diabetes in sub-Saharan Africa.Frontiers in public health · 2023Review
- COVID-19 and diabetic ketoacidosis: A case series at an urban district hospital in South Africa.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2022Article
- Clinical characteristics of people with diabetic ketoacidosis at a clinic in The Gambia: a retrospective study.JEMDSA : the journal of endocrinology, metabolism and diabetes of South Africa (JEMDSA) : the official journal of the Society of Endocrinology, Metabolism and Diabetes of South Africa · 2022Article
- Treatment outcomes of diabetic ketoacidosis among diabetes patients in Ethiopia. Hospital-based study.PloS one · 2022Article
- The burden of diabetic emergencies on the resuscitation area of a district-level public hospital in Cape Town.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2021Article
- Detection and analysis of glucose metabolism-related genes in childhood diabetes using targeted next-generation sequencing: In pediatric population-a hospital-based study.Experimental and therapeutic medicine · 2020Article
- The Corrected Serum Sodium Concentration in Hyperglycemic Crises: Computation and Clinical Applications.Frontiers in medicine · 2020Article
- Sepsis in Latent Autoimmune Diabetes in Adults with Diabetic Ketoacidosis: A Case Report.Open access Macedonian journal of medical sciences · 2019Article
- Management of Diabetic Ketoacidosis in Adults: A Narrative Review.Saudi journal of medicine & medical sciencesReview
- Incidence, characteristics and long-term outcomes of patients with diabetic ketoacidosis: a prospective prognosis cohort study in an emergency department.Sao Paulo medical journal = Revista paulista de medicinaArticle
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Authors and funding
2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundDiabetic ketoacidosis (DKA) is a biochemical triad of hyperglycaemia, ketoacidosis and ketonaemia and one of the potentially life-threatening acute metabolic complications of diabetes mellitus. This study aimed at describing the clinical profile of patients presenting with DKA to a busy rural regional hospital in KwaZulu-Natal.
methodsA retrospective review of clinical notes of patients presenting with DKA to the Emergency Department was performed over a 10-month period. Data included patients' demographic profile, clinical presentation, precipitating factors, comorbidities, biochemical profile, length of hospital stay and outcome.
resultsOne hundred and five black South African patients above the age of 12 years were included in the study. Sixty-four (60.95%) patients had type 1 diabetes mellitus (T1DM) and 41 (39.05%) patients had type 2 diabetes mellitus (T2DM). Patients with T2DM were significantly older than those with T1DM (52.1 ± 12.4 years vs. 24.4 ± 9.5 years, p < 0.0001). The acute precipitant was identified in 68 (64.76%) cases with the commonest precipitant in T1DM patients being poor adherence to treatment, whereas in T2DM, the most common precipitant was infection. Nausea and vomiting were the most common presenting symptoms with the majority of patients presenting with non-specific symptoms. Fifty-seven (54.29%) cases had pre-existing comorbidities, with higher prevalence in T2DM than T1DM patients. Glycated haemoglobin was severely elevated in the majority of patients. Patients remained hospitalised for an average of 8.9 ± 7.5 days. The mortality rate was 17.14%, and 12 of the 18 deaths occurred in patients with T2DM.
conclusionThe prevalence of DKA was higher in patients with T1DM and those with pre-existing comorbidities. The mortality rate remains alarmingly high in older patients with T2DM.
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