Evidence map›Paper›PMID 29781657›Full record

ArticleJournal of abnormal psychology2018

Longitudinal stability of cognitive control in early psychosis: Nondegenerative deficits across diagnoses.

Jason Smucny, Tyler A Lesh, Ana-Maria Iosif, Tara A Niendam, Laura M Tully, Cameron S Carter

Open access · hybridAbstract read
In one paragraph

Article in Journal of abnormal psychology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  8. Mechanisms underlying dorsolateral prefrontal cortex contributions to cognitive dysfunction in schizophrenia.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jason SmucnyDepartment of Psychiatry and Behavioral Sciences, University of California, Davis.ORCID 0000-0001-5656-7987
Tyler A LeshDepartment of Psychiatry and Behavioral Sciences, University of California, Davis.ORCID 0000-0002-6160-3927
Ana-Maria IosifDepartment of Public Health Sciences, University of California, Davis.
Tara A NiendamDepartment of Psychiatry and Behavioral Sciences, University of California, Davis.ORCID 0000-0003-2285-5002
Laura M TullyDepartment of Psychiatry and Behavioral Sciences, University of California, Davis.
Cameron S CarterDepartment of Psychiatry and Behavioral Sciences, University of California, Davis.
University of California, Davis · US

Funding

Building Interdisciplinary Research Careers in Womens Health at UC Davis - Administrative SupplementK12HD051958 · NICHD · UNIVERSITY OF CALIFORNIA DAVIS · PI LANE, NANCY E · 2005 to 2023
$9.6M
PATHOPHYSIOLOGY OF COGNITIVE DISABILITY IN SCHIZOPHRENIAR01MH059883 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CARTER, CAMERON S. · 2000 to 2017
$6.1M
The effects of transcranial direct current stimulation on the neuronal mechanisms of cognitive control in schizophreniaF32MH114325 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SMUCNY, JASON · 2017 to 2019
$176k
National Institute of AgingNational Institute of Child Health and Human Development; Office of Research on Women's Health; Office of Dietary SupplementsNational Institutes of HealthNational Institutes of Mental HealthNICHD NIH HHS K12 HD051958NIMH NIH HHS F32 MH114325NIMH NIH HHS R01 MH059883
6 · The paper itself

Abstract

Cognitive impairment, particularly in the domain of cognitive control, is characteristic of schizophrenia (SZ) spectrum and bipolar disorders (BDs). The longitudinal trajectory of these impairments, however, remains unclear. Indeed, some studies have observed degeneration and others stability or even improvement over time in these illnesses. Here we examined the longitudinal stability of the AX-Continuous Performance Task (AX-CPT), a cognitive control task, in 52 patients with recent-onset SZ (<2 years from first study measurement), 20 patients with recent-onset BD Type I with psychotic features, and 70 healthy control subjects. Subjects performed the AX-CPT at 2 time points separated by an average of 365 days (range 270-620). Previously identified deficits in cognitive control were replicated in both patient groups. No effects of time or interactions between time and diagnosis were observed. Intraclass correlation coefficients also suggested AX-CPT performance was stable across time for all diagnostic groups. Although performance was stable on average, a positive association was noted between change in cognitive control and change in disorganization symptom severity across patient groups. In conclusion, the present findings suggest that deficits in cognitive control are present in both disorders and stable over the early course of psychotic illness. No evidence was observed for progression or deterioration of cognitive control or differential recovery in SZ compared to BD. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Indexed as

Executive FunctionSchizophrenic PsychologyAdolescentAdultBipolar DisorderDisease ProgressionFemaleHumansMaleNeuropsychological TestsPsychotic DisordersSchizophreniaYoung Adult

Identifiers

PMID29781657
PMCPMC6237622
OpenAlexW2804531579

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.