Evidence map›Paper›PMID 29781180›Full record

Trial reportJournal of applied behavior analysis2018

Identifying predictive behavioral markers: A demonstration using automatically reinforced self-injurious behavior.

Louis P Hagopian, Griffin W Rooker, Gayane Yenokyan

Abstract readClinical Trial
In one paragraph

Trial report in Journal of applied behavior analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Prevalence of Error Types of Synthesized Contingency Assessments.Behavior analysis (Washington, D.C.) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. A scoping review of consecutive controlled case series studies.Journal of applied behavior analysis · 2025
    Article
  8. Review
  9. Review
  10. Bouts, Pauses, and Units of Operant Performance: A Primer.Perspectives on behavior science · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. A Neurobehavioral Continuum of Care for Individuals with Intellectual and Developmental Disabilities with Severe Problem Behavior.Children's health care : journal of the Association for the Care of Children's Health · 2023
    Article
  18. Article
  19. Decreasing motor stereotypy with competing stimuli and tasks: Analysis of prompted engagement and response blocking.Behavioral interventions : theory & practice in residential & community-based clinical programs · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Louis P HagopianThe Kennedy Krieger Institute.
Griffin W RookerThe Kennedy Krieger Institute.
Gayane YenokyanJohns Hopkins University Bloomberg School of Public Health.

Funding

Translational Neuroscience CoreU54HD079123 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI FATEMI, S. ALI, SCHLAGGAR, BRADLEY L · 2014 to 2019
$7.9M
Delineating Subtypes of Self-Injurious Behavior Maintained by Automatic ReinforceR01HD076653 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI HAGOPIAN, LOUIS P. · 2013 to 2024
$3.2M
NICHD NIH HHS R01 HD076653NICHD NIH HHS U54 HD079123
6 · The paper itself

Abstract

Predictive biomarkers (PBioMs) are objective biological measures that predict response to medical treatments for diseases. The current study translates methods used in the field of precision medicine to identify PBioMs to identify parallel predictive behavioral markers (PBMs), defined as objective behavioral measures that predict response to treatment. We demonstrate the utility of this approach by examining the accuracy of two PBMs for automatically reinforced self-injurious behavior (ASIB). Results of the analysis indicated both functioned as good to excellent PBMs. We discuss the compatibility of this approach with applied behavior analysis, describe methods to identify additional PBMs, and posit that variables related to the mechanisms of problem behavior and putative mechanism of treatment action hold the most promise as potential PBMs. We discuss how this technology could guide individualized treatment selection, inform our understanding of problem behavior and mechanisms of treatment action, and help determine the conditional effectiveness of clinical procedures.

Indexed as

EndophenotypesAdolescentBehavior TherapyChildChild, PreschoolFemaleHumansMaleSelf-Injurious BehaviorSensitivity and SpecificityTreatment OutcomeYoung Adultautomatically reinforced self-injurious behaviorconditional effectivenessconditional probability analysisprecision medicinepredictive behavioral markers

Identifiers

PMID29781180
PMCPMC7269171

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.