Evidence map›Paper›PMID 29781044›Full record

ArticleObesity surgery2018

Sleeve Gastrectomy in Morbidly Obese HIV Patients: Focus on Anti-retroviral Treatment Absorption After Surgery.

Chloé Amouyal, Marion Buyse, Lea Lucas-Martini, Déborah Hirt, Laurent Genser, Adriana Torcivia, Jean-Luc Bouillot, Jean-Michel Oppert, Judith Aron-Wisnewsky

Abstract read
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In one paragraph

Article in Obesity surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. The influence of bariatric surgery on oral drug bioavailability in patients with obesity: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2019
    Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. NASH in HIV.Current HIV/AIDS reports · 2020
    Review
  11. HIV and antiretroviral therapy-related fat alterations.Nature reviews. Disease primers · 2020
    Review
  12. Canadian family physician Medecin de famille canadien · 2020
    Review
  13. Medication management and pharmacokinetic changes after bariatric surgery.Canadian family physician Medecin de famille canadien · 2020
    Review
  14. Obesity and Weight Gain in Persons with HIV.Current HIV/AIDS reports · 2020 · on this map
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Chloé AmouyalINSERM, UMRS, NutriOmicsTeam, Sorbonne Université, Paris, France.
Marion BuyseINSERM, Saint-Antoine Research Center, Saint-Antoine Hospital, Sorbonne Université, Paris, France.
Lea Lucas-MartiniNutrition Department, Pitié-Salpêtrière Hospital, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Paris, France.
Déborah HirtINSERM, Saint-Antoine Research Center, Saint-Antoine Hospital, Sorbonne Université, Paris, France.
Laurent GenserINSERM, UMRS, NutriOmicsTeam, Sorbonne Université, Paris, France.
Adriana TorciviaVisceral Surgery Department, Pitié-Salpêtrière Hospital, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Paris, France.
Jean-Luc BouillotVisceral Surgery Department, Ambroise Paré Hospital, Assistance Publique Hôpitaux de Paris, Saint Quentin Versailles University, Paris, France.
Jean-Michel OppertInstitute of Cardiometabolism and Nutrition, Institut E3M, 83 boulevard de l'Hôpital, 75013, Paris, France.
Judith Aron-WisnewskyINSERM, UMRS, NutriOmicsTeam, Sorbonne Université, Paris, France. judith.aron-wisnewsky@aphp.fr.ORCID 0000-0002-3104-9769
Inserm · FRSorbonne Université · FRAssistance Publique – Hôpitaux de Paris · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextAnti-retroviral therapy (ART) dramatically reduced AIDS development, thus enabling patients to live as long as the general population. New challenges have emerged particularly cardiometabolic diseases and weight gain, with some HIV patients seeking bariatric surgery (BS). However, BS outcomes during HIV remain poorly described, with scarce data on ART pharmacokinetic post-BS.

objectiveDescribing sleeve gastrectomy (SG) results in HIV patients in terms of ART pharmacokinetic, HIV control, weight loss, and metabolic outcomes. DESIGN, SETTING, AND PATIENTS: Prospective study of HIV patients undergoing SG in a referral academic center, with at least 6 months follow-up.

main outcome measureClinical and biological parameters, HIV medical history, and ART pharmacokinetics were gathered before and post-SG.

resultsSeventeen patients (mean BMI = 44.2 ± 5.7 kg m

conclusionsSG seems effective and safe in obese HIV patients. However, ART treatment should be monitored post-SG to control HIV infection. We suggest that some ART should be adapted before SG conjoints with infectious disease specialists.

Indexed as

Bariatric SurgeryIntestinal AbsorptionAdultAnti-Retroviral AgentsFemaleFollow-Up StudiesHIVHIV InfectionsHumansLaparoscopyMalabsorption SyndromesMaleMiddle AgedObesity, MorbidPostoperative ComplicationsProspective StudiesAnti-Retroviral AgentsAnti-retroviral therapyBariatric surgeryHIVPharmacokineticsSleeve gastrectomy

Identifiers

PMID29781044
OpenAlexW2804788159

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.