Evidence map›Paper›PMID 29780946›Full record

ArticleAmerican journal of ophthalmology case reports2018

Bilateral acute depigmentation of the iris in two siblings simultaneously.

Rana Amin, Amena Nabih, Noha Khater

Open access · goldAbstract read
In one paragraph

Article in American journal of ophthalmology case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Commentary: Bilateral acute depigmentation of iris.Indian journal of ophthalmology · 2019
    Article
  5. Bilateral acute depigmentation of iris.Indian journal of ophthalmology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rana AminDepartment of Ophthalmology, Faculty of Medicine, Kasr El Aini Hospital, Cairo University, 1 Kasr El Aini Street, Al Manial, Cairo, Egypt.
Amena NabihAl Mouneer Center for Diabetic Eye Care, 92 El Tharir Street, 4th Floor, Giza, Egypt.
Noha KhaterDepartment of Ophthalmology, Faculty of Medicine, Kasr El Aini Hospital, Cairo University, 1 Kasr El Aini Street, Al Manial, Cairo, Egypt.
Cairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report the first simultaneous onset of bilateral acute depigmentation of the iris (BADI) in two siblings. OBSERVATIONS: Two sisters presented with bilateral ocular pain, redness and light sensitivity. Examination revealed bilateral circulating pigment in the anterior chamber with pigment dusting on backs of the corneas, patchy iris depigmentation and heavy pigment deposition in the angle. Both patients had recently suffered from upper respiratory tract infections. Bilateral visual acuities were preserved and no transillumination defects were observed. The patients were diagnosed with BADI. Both cases were successfully controlled with topical corticosteroids and anti-glaucoma drops as well as topical glanciclovir gel. CONCLUSIONS AND IMPORTANCE: To date, there had been no published reports of BADI in the Middle East and Africa. This is the first observation of this entity in these regions. Moreover it is the first occurrence of BADI in two immediate siblings simultaneously. We also report the rare asymmetrical presentation with BADI in one of our patients. These observations point to the possibility of genetic factors underlying BADI as well as an infectious cause behind the etiology.

Indexed as

AcuteDepigmentationGonioscopyKrukenbergPigment dispersionSymmetrical

Identifiers

PMID29780946
PMCPMC5956750
OpenAlexW2791228916

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.