Evidence map›Paper›PMID 29780942›Full record

ArticleAmerican journal of ophthalmology case reports2018

Successful reconstruction of an ocular defect resulting from granulomatosis with polyangiitis, following treatment with rituximab.

Grace M Kenny, Konstanze Holl-Ulrich, Timothy Fulcher, Elizabeth McElnea, Eoin Kavanagh, Heather Moriarty, Niall Mulligan, Eamonn S Molloy, Geraldine M McCarthy

Open access · goldAbstract readCase Reports
In one paragraph

Article in American journal of ophthalmology case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Imaging analysis of ocular involvement in granulomatosis with polyangiitis.Quantitative imaging in medicine and surgery · 2024
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Grace M KennyMater Misericordiae University Hospital, Eccles St, Dublin 7, Ireland.
Konstanze Holl-UlrichInstitute of Pathology, MVZ am Marienkrankenhaus Hamburg, Germany.
Timothy FulcherMater Misericordiae University Hospital, Eccles St, Dublin 7, Ireland.
Elizabeth McElneaMater Misericordiae University Hospital, Eccles St, Dublin 7, Ireland.
Eoin KavanaghMater Misericordiae University Hospital, Eccles St, Dublin 7, Ireland.
Heather MoriartyMater Misericordiae University Hospital, Eccles St, Dublin 7, Ireland.
Niall MulliganMater Misericordiae University Hospital, Eccles St, Dublin 7, Ireland.
Eamonn S MolloySt Vincents University Hospital, Elm Park, Dublin 4, Ireland.
Geraldine M McCarthyMater Misericordiae University Hospital, Eccles St, Dublin 7, Ireland.
Mater Misericordiae University Hospital · IEMarienkrankenhaus Hamburg · DESt. Vincent's University Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report a unique case of orbital inflammatory disease which was ultimately diagnosed as granulomatosis with polyangitis (GPA) and thus successfully treated. OBSERVATION: A 47 year-old man presented with a rapidly progressive necrotic soft tissue mass within the medial antero-superior aspect of the right eyelid and orbit. He also had transient retinal vasculitis in the left. Serology, histology and imaging were atypical of, but consistent with, GPA. He was thus successfully treated with intravenous rituximab followed by reconstruction of the medial eyelid. CONCLUSION AND IMPORTANCE: A high index of suspicion of GPA is required in orbital inflammatory disease, especially when typical diagnostic findings are absent.

Indexed as

Eyelid reconstructionGranulomatosis with polyangiitisOrbital inflammatory diseaseRituximab

Identifiers

PMID29780942
PMCPMC5956741
OpenAlexW2794275894

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.