Evidence map›Paper›PMID 29780879›Full record

ArticleeNeuro

Altered Cerebellar Short-Term Plasticity but No Change in Postsynaptic AMPA-Type Glutamate Receptors in a Mouse Model of Juvenile Batten Disease.

Dorota Studniarczyk, Elizabeth L Needham, Hannah M Mitchison, Mark Farrant, Stuart G Cull-Candy

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Reversible synaptic deficits in early-stage batten disease.Journal of translational medicine · 2026
    Article
  2. Aging, Neurodegenerative Disorders, and Cerebellum.International journal of molecular sciences · 2024
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Dorota StudniarczykDepartment of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, United Kingdom.ORCID 0000-0003-4109-7956
Elizabeth L NeedhamDepartment of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, United Kingdom.
Hannah M MitchisonUCL Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, United Kingdom.
Mark FarrantDepartment of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, United Kingdom.ORCID 0000-0002-9918-0376
Stuart G Cull-CandyDepartment of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, United Kingdom.ORCID 0000-0002-0831-8326
University College London · GBGreat Ormond Street Hospital · GB

Funding

Biotechnology and Biological Sciences Research Council BB/D526961/1Medical Research Council MR/J002976/1Medical Research Council MR/J012998/1Wellcome TrustWellcome Trust 086185/Z/08/Z
6 · The paper itself

Abstract

Juvenile Batten disease is the most common progressive neurodegenerative disorder of childhood. It is associated with mutations in the

Indexed as

AnimalsCerebellumDisease Models, AnimalMembrane GlycoproteinsMiceMice, Inbred C57BLMice, KnockoutMolecular ChaperonesNeuronal Ceroid-LipofuscinosesNeuronal PlasticityPatch-Clamp TechniquesReceptors, AMPACLN3 protein, mouseMembrane GlycoproteinsMolecular ChaperonesReceptors, AMPAAMPA receptorsBatten diseasecerebellumCLN3EPSCsshort-term plasticity

Identifiers

PMID29780879
PMCPMC5956745
OpenAlexW2800236408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.