Evidence map›Paper›PMID 29780759›Full record

ArticleJournal of clinical and diagnostic research : JCDR2018

Para-Substituted Functionalised Ferrocene Esters with Novel Antibacterial Properties.

Kevin Muñoz Forti, Faviola Bernard, Gustavo Santiago-Collazo, Waldemar Garcia, Jose L Vera, Enrique Meléndez, Edu B Suarez-Martinez

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Kevin Muñoz FortiGraduate Student, Department of Biotechnology, Pontifical Catholic University of Puerto Rico, Ponce PR 00731; Research Coordinator, Department of Biology, University of Puerto Rico, Ponce PR 00716.
Faviola BernardStudent, Department of Biology, University of Puerto Rico, Ponce PR 00716.
Gustavo Santiago-CollazoStudent, Department of Biology, University of Puerto Rico, Ponce PR 00716.
Waldemar GarciaTechnician, Department of Biology, University of Puerto Rico, Ponce PR 00716.
Jose L VeraProfessor, Department of Chemistry, University of Puerto Rico, Mayagüez PR 00681; Inter American University of San German Biology, Chemistry, and Environmental Science Department Calle Luna, San Germán 00683.
Enrique MeléndezProfessor, Inter American University of San German Biology, Chemistry, and Environmental Science Department Calle Luna, San Germán 00683.
Edu B Suarez-MartinezProfessor, Department of Biology, University of Puerto Rico, Ponce PR 00716; Professor, Ponce Research Institute, Ponce Health Sciences University, Ponce, Puerto Rico 00732.
University of Puerto Rico at Ponce · PRInterAmerican University of Puerto Rico · PRPonce Health Sciences University · PRPontifical Catholic University of Puerto Rico · PR

Funding

UNIVERSITY OF PUERTO RICO PONCE RESEARCH INITIATIVE FOR SCIENTIFIC ENHANCEMENT: UR25GM096955 · NIGMS · UNIVERSITY OF PUERTO RICO PONCE · PI SUAREZ-MARTINEZ, EDU B · 2011 to 2020
$5.7M
NIGMS NIH HHS R25 GM096955
6 · The paper itself

Abstract

introductionBacterial antibiotic resistance is on rise despite advances in the development of new antibiotics. In an attempt to circumvent resistance, scientists are shifting focus from modifying existent antibiotics to identifying new antibiotic compounds.

aimTo assess the potential antibiotic effects of functionalised ferrocenecarboxylates para-substituted on the phenoxy pendant group to form: 4-fluorophenyl, 4-chlorophenyl, 4-bromophenyl, 4-iodophenyl and 4-(H-pyrrol-1-yl)phenyl. MATERIALS AND

methodsFor this, we employed the Kirby-Bauer disc diffusion method using a collection of nine bacterial species:

resultsThe results show that all four-halogen substituted

conclusionHence, functionalised ferrocenecarboxylates para-substituted with small and simple groups represent a novel class of bio-organometallic compounds with the potential to be used as antibacterial agents.

Indexed as

AntibacterialBio-organometallic compoundsFerrocenecarbolylatePhenoxy pendant

Identifiers

PMID29780759
PMCPMC5958608
OpenAlexW2790947506

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.