Evidence map›Paper›PMID 29780644›Full record

ArticleCase reports in dentistry2018

Spindle Cell Hemangioma in the Mucosa of the Upper Lip: A Case Report and Review of the Literature.

Kazuhiro Murakami, Kazuhiko Yamamoto, Tsutomu Sugiura, Tadaaki Kirita

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in dentistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Immunohistochemical Analysis of Oral Spindle Cell Hemangioma.Journal of dentistry (Shiraz, Iran) · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Spindle cell haemangioma - Report of a rare entity.Journal of oral and maxillofacial pathology : JOMFP
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kazuhiro MurakamiDepartment of Oral and Maxillofacial Surgery, Nara Medical University, Kashihara, Nara, Japan.ORCID 0000-0002-2144-5020
Kazuhiko YamamotoDepartment of Oral and Maxillofacial Surgery, Nara Medical University, Kashihara, Nara, Japan.ORCID 0000-0002-9931-889X
Tsutomu SugiuraDepartment of Oral and Maxillofacial Surgery, Nara Medical University, Kashihara, Nara, Japan.
Tadaaki KiritaDepartment of Oral and Maxillofacial Surgery, Nara Medical University, Kashihara, Nara, Japan.
Nara Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spindle cell hemangioma (SCH) is a unique benign vascular lesion. We present a case of SCH in the upper lip of a 41-year-old woman. A submucosal nodular mass 30 × 20 mm in size was observed in the left upper lip. The mass developed 5 years earlier and enlarged after repeated ethanol injections. The mass was elastic firm, mobile, bluish in color, and well demarcated in magnetic resonance imaging. Under the clinical diagnosis of hemangioma, surgical excision was performed under local anesthesia. Microscopically, the lesion was composed of irregular cavernous spaces and multiple solid cellular areas. Cavernous spaces were filled with a mix of erythrocytes and organizing thrombi. The solid areas showed proliferation of spindle-shaped cells arranged haphazardly or in short interlacing fascicles. Immunohistochemically, most cells strongly reacted with vimentin. CD31, CD34, factor VIII, smooth muscle actin, and Wilms tumor-1 reacted with endothelial cells lining the cavernous spaces. The cells within solid areas consisted of mixed cell population with variable reaction for the markers except for factor VIII. From these findings, the diagnosis of SCH was made. Two years after surgery, no recurrence was noted. A review of SCH in the head and neck region is made.

Identifiers

PMID29780644
PMCPMC5892276
OpenAlexW2794291318

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.