ArticleEFORT open reviews2018
Thromboembolism prophylaxis in orthopaedics: an update.
Article in EFORT open reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 102 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Prophylactic Anticoagulation on Major Bleeding Events in Hospitalized Chronic Kidney Disease and Lower Limb Fracture Patients. a Phase 2, Randomized, Doble Blind, Control Trial
The Effect of Cold Spray Application in Reducing Pain and Ecchymosis in Patients Receiving Low Molecular Weight Heparin Prophylaxis After Orthopedic Surgery
Who cites it
102 citing papers in PubMed, 4 syntheses or guidelines pooled it, 223 citations in OpenAlex.
- Impact of extended duration pharmacological thromboprophylaxis on venous thromboembolism after hip and knee arthroplasty and hip fracture surgery: a systematic review and meta-analysis of randomised controlled trials.Journal of thrombosis and thrombolysis · 2026Pooled it
- Low-versus high-dose aspirin for venous thromboembolic prophylaxis after total joint arthroplasty: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2024Pooled it
- Aspirin for prophylaxis of VTE in patients with Hip/ Knee replacement: Systematic review and Meta-analysis of Non-Randomized studies.Indian journal of pharmacology · 2024Pooled it
- Aspirin is a safe and effective thromboembolic prophylaxis after total knee arthroplasty: a systematic review and meta-analysis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Pooled it
- Trial
- Effects of Continuous Graduated Pneumatic Compression and Intermittent Pneumatic Compression on Lower Limb Hemodynamics for VTE Prophylaxis in Arthroplasty.Orthopaedic surgery · 2025Trial
- Trial
- Impact of compression stockings on leg swelling after arthroscopy - a prospective randomised pilot study.BMC musculoskeletal disorders · 2019Trial
- Similar thromboprophylaxis with rivaroxaban and low molecular weight heparin but fewer hemorrhagic complications with combined intra-articular and intravenous tranexamic acid in total knee arthroplasty.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2019Trial
- Symptomatic Deep Vein Thrombosis Following Elective Knee Arthroscopy Over the Age of 40.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisTrial
- Estrogen hormonal therapy is not associated with increased risk of venous thrombosis in total hip arthroplasty or hemiarthroplasty for femoral neck fractures.OTA international : the open access journal of orthopaedic trauma · 2026Article
- Antibiofilm-coated intramedullary nailing for tibial and femoral diaphyseal fractures at high-risk infection: outcomes of 103 consecutive patients.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2026Observational
- Aspirin for Venous Thromboembolism Prevention in Orthopaedic Surgery with Focus on Trauma and Arthroplasty: A Structured Evidence-Based Review of Randomised Trials, Guidelines, and Contemporary Practice Considerations.Journal of clinical medicine · 2026Review
- Article
- Exploring intermittent pneumatic compression parameters to optimize venous peak velocity and flow duration.Scientific reports · 2026Article
- Comparison of clinical outcomes of enoxaparin and aspirin for postoperative venous thromboembolism prophylaxis in hip fractures.Acta orthopaedica et traumatologica turcica · 2026Article
- Artificial Intelligence in Venous Thromboembolism Prevention: A Narrative Review of Machine Learning, Deep Learning, and Natural Language Processing.Journal of cardiovascular development and disease · 2026Review
- Outcome Analysis of Single Stage Total Knee Arthroplasty with Long Tibial Stem in Complex Primary Osteoarthritis with Tibia Stress Fracture.Malaysian orthopaedic journal · 2026Article
- Beyond Overuse: A Cross-Sectional Analysis of Insulin Resistance in De Quervain's and Stenosing Flexor Tenosynovitis.Malaysian orthopaedic journal · 2026Article
- Clinical pharmacology of antiplatelet drugs: implications for personalized therapy.European journal of clinical pharmacology · 2026Review
42 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Venous thromboembolism (VTE) is a serious complication during and after hospitalization, yet is a preventable cause of in-hospital death.Without VTE prophylaxis, the overall VTE incidence in medical and general surgery hospitalized patients is in the range of 10% to 40%, while it ranges up to 40% to 60% in major orthopaedic surgery. With routine VTE prophylaxis, fatal pulmonary embolism is uncommon in orthopaedic patients and the rates of symptomatic VTE within three months are in the range of 1.3% to 10%.VTE prophylaxis methods are divided into mechanical and pharmacological. The former include mobilization, graduated compression stockings, intermittent pneumatic compression device and venous foot pumps; the latter include aspirin, unfractionated heparin, low molecular weight heparin (LMWH), adjusted dose vitamin K antagonists, synthetic pentasaccharid factor Xa inhibitor (fondaparinux) and newer oral anticoagulants. LMWH seems to be more efficient overall compared with the other available agents. We remain sceptical about the use of aspirin as a sole method of prophylaxis in total hip and knee replacement and hip fracture surgery, while controversy still exists regarding the use of VTE prophylaxis in knee arthroscopy, lower leg injuries and upper extremity surgery. Cite this article:
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.