Evidence map›Paper›PMID 29780583›Full record

ArticleRSC advances2018

Exploring local solvation environments of a heme protein using the spectroscopic reporter 4-cyano-l-phenylalanine.

Caroline Kearney, Lukasz T Olenginski, Trexler D Hirn, Gwendolyn D Fowler, Daniyal Tariq, Scott H Brewer, Christine M Phillips-Piro

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Extending the vibrational lifetime of azides with heavy atoms.Physical chemistry chemical physics : PCCP · 2020
    Article
  4. Review
  5. Article
  6. Crystal structures of green fluorescent protein with the unnatural amino acid 4-nitro-L-phenylalanine.Acta crystallographica. Section F, Structural biology communications · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Caroline KearneyDepartment of Chemistry, Franklin & Marshall College, PO Box 3003, Lancaster, PA 17604-3003, USA. Email: sbrewer@fandm.edu; Email: cpiro@fandm.edu.
Lukasz T OlenginskiDepartment of Chemistry, Franklin & Marshall College, PO Box 3003, Lancaster, PA 17604-3003, USA. Email: sbrewer@fandm.edu; Email: cpiro@fandm.edu.
Trexler D HirnDepartment of Chemistry, Franklin & Marshall College, PO Box 3003, Lancaster, PA 17604-3003, USA. Email: sbrewer@fandm.edu; Email: cpiro@fandm.edu.
Gwendolyn D FowlerDepartment of Chemistry, Franklin & Marshall College, PO Box 3003, Lancaster, PA 17604-3003, USA. Email: sbrewer@fandm.edu; Email: cpiro@fandm.edu.
Daniyal TariqDepartment of Chemistry, Franklin & Marshall College, PO Box 3003, Lancaster, PA 17604-3003, USA. Email: sbrewer@fandm.edu; Email: cpiro@fandm.edu.
Scott H BrewerDepartment of Chemistry, Franklin & Marshall College, PO Box 3003, Lancaster, PA 17604-3003, USA. Email: sbrewer@fandm.edu; Email: cpiro@fandm.edu.
Christine M Phillips-PiroDepartment of Chemistry, Franklin & Marshall College, PO Box 3003, Lancaster, PA 17604-3003, USA. Email: sbrewer@fandm.edu; Email: cpiro@fandm.edu.ORCID 0000-0002-7335-7487
Franklin & Marshall College · US

Funding

Overall EvaluationP41GM103403 · NIGMS · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2012 to 2017
$14.3M
Pixel Array Detector for Macromolecular CrystallographyS10OD021527 · OD · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2016 to 2016
$2.0M
Monitoring and Tuning a Gas-Binding Heme Protein with Unnatural Amino AcidsR15GM121984 · NIGMS · FRANKLIN AND MARSHALL COLLEGE · PI PIRO, CHRISTINE MARIE PHILLIPS · 2016 to 2016
$372k
NIGMS NIH HHS P41 GM103403NIGMS NIH HHS R15 GM121984NIH HHS S10 OD021527
6 · The paper itself

Abstract

The vibrational reporter unnatural amino acid (UAA) 4-cyano-l-phenylalanine (pCNF) was genetically incorporated individually at three sites (5, 36, and 78) in the heme protein

Identifiers

PMID29780583
PMCPMC5944249
OpenAlexW2797654249

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.