Evidence map›Paper›PMID 29780560›Full record

ArticleChemical science2018

Counting charges on membrane-bound peptides.

Alicia C McGeachy, Emily R Caudill, Dongyue Liang, Qiang Cui, Joel A Pedersen, Franz M Geiger

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. The polybasic puzzle: how N-terminal charges modulate GαiCell communication and signaling : CCS · 2025
    Article
  2. Article
  3. Review
  4. Water at charged interfaces.Nature reviews. Chemistry · 2021
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alicia C McGeachyDepartment of Chemistry , Northwestern University , 2145 Sheridan Road , Evanston , IL 60660 , USA . Email: geigerf@chem.northwestern.edu.ORCID 0000-0003-1519-308X
Emily R CaudillDepartment of Chemistry , University of Wisconsin-Madison , 1101 University Avenue , Madison , WI 53706 , USA.ORCID 0000-0002-3645-9804
Dongyue LiangDepartment of Chemistry , University of Wisconsin-Madison , 1101 University Avenue , Madison , WI 53706 , USA.
Qiang CuiDepartment of Chemistry , University of Wisconsin-Madison , 1101 University Avenue , Madison , WI 53706 , USA.ORCID 0000-0001-6214-5211
Joel A PedersenDepartment of Chemistry , University of Wisconsin-Madison , 1101 University Avenue , Madison , WI 53706 , USA.ORCID 0000-0002-3918-1860
Franz M GeigerDepartment of Chemistry , Northwestern University , 2145 Sheridan Road , Evanston , IL 60660 , USA . Email: geigerf@chem.northwestern.edu.ORCID 0000-0001-8569-4045

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quantifying the number of charges on peptides bound to interfaces requires reliable estimates of (i) surface coverage and (ii) surface charge, both of which are notoriously difficult parameters to obtain, especially at solid/water interfaces. Here, we report the thermodynamics and electrostatics governing the interactions of l-lysine and l-arginine octamers (Lys

Identifiers

PMID29780560
PMCPMC5944241

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.