ArticleChemical science2018
A halogen bond-mediated highly active artificial chloride channel with high anticancer activity.
Article in Chemical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 135 citations in OpenAlex.
- Chloride-Selective Transmembrane Channel Formation byJACS Au · 2026Article
- XAI-ACSM: An Ensemble-Based Explainable Artificial Intelligence Framework for the Accurate Prediction of Anticancer Small Molecules.ACS omega · 2025Article
- Medical and Nonmedical Applications of Synthetic Transmembrane Anion Transporters.Chemical reviews · 2025Review
- Highly Selective Artificial KJACS Au · 2024Article
- Naphthalene Diimide-Based Metallacage as an Artificial Ion Channel for Chloride Ion Transport.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- An Exceptionally Active and Highly Selective Perchlorate Transporter Containing a Trimesic Amide Scaffold.Molecules (Basel, Switzerland) · 2024Article
- Limitations of non-polarizable force fields in describing anion binding poses in non-polar synthetic hosts.Physical chemistry chemical physics : PCCP · 2023Article
- Halogen bonding relay and mobile anion transporters with kinetically controlled chloride selectivity.Chemical science · 2023Article
- Formation of supramolecular channels by reversible unwinding-rewinding of bis(indole) double helix via ion coordination.Nature communications · 2022Article
- Cholesterol-stabilized membrane-active nanopores with anticancer activities.Nature communications · 2022Article
- Calix[6]arenes with halogen bond donor groups as selective and efficient anion transporters.Chemical communications (Cambridge, England) · 2022Article
- Ion Channels and Transporters as Therapeutic Agents: From Biomolecules to Supramolecular Medicinal Chemistry.Biomedicines · 2022Review
- Pnictogen-Bonding Catalysis and Transport Combined: Polyether Transporters Made In Situ.JACS Au · 2021Article
- Recent Advances in Bioactive Artificial Ionophores.Chembiochem : a European journal of chemical biology · 2021Review
- Highly Active Halogen Bonding and Chalcogen Bonding Chloride Transporters with Non-Protonophoric Activity.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Article
- Foldamer-based ultrapermeable and highly selective artificial water channels that exclude protons.Nature nanotechnology · 2021Article
- Switchable foldamer ion channels with antibacterial activity.Chemical science · 2020Article
- Transmembrane anion transport mediated by halogen bonding and hydrogen bonding triazole anionophores.Chemical science · 2020Article
- Polyhydrazide-Based Organic Nanotubes as Efficient and Selective Artificial Iodide Channels.Angewandte Chemie (International ed. in English) · 2020Article
- Apoptosis-inducing activity of a fluorescent barrel-rosette MChemical science · 2020Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chloride-selective transmembrane carriers or channels might have possible uses in treating channelopathies or cancers. While chloride carriers have been extensively investigated, the corresponding chloride channels have remained limitedly studied. Moreover, all hitherto reported channel systems lack clearly definable and readily modifiable positions in their structures for the reliable construction and combinatorial optimization of their ion transport properties. As a result, the existing channels are limited by their large molecular weight, weak activity or low anion selectivity. In this report, we describe a readily accessible and robust monopeptide-based scaffold for the reliable construction of halogen bond-mediated artificial anion channels
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.