ArticleChemical science2017
Photoactivatable aggregation-induced emission probes for lipid droplets-specific live cell imaging.
Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Lipid droplet dynamics in metabolic regulation.RSC chemical biology · 2026Review
- From Spark to Flame: ROS- and Light-Cascade Activatable NIR-II AIE Probe for Precise Tumor Imaging and Self-Amplifying Phototherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Construction of the 4-Azafluorenone Core in a Single Operation and Synthesis of Onychine.The Journal of organic chemistry · 2024Article
- Molecular Deformation Is a Key Factor in Screening Aggregation Inhibitor for Intrinsically Disordered Protein Tau.ACS central science · 2024Article
- A Multifunctional Aggregation-Induced Emission Luminogen with pH-Response Detachable Connector for Lipid Droplet-Specific Imaging and Tracing.Molecules (Basel, Switzerland) · 2023Article
- Aggregation-Induced Emission (AIE), Life and Health.ACS nano · 2023Review
- Biomaterials and Encapsulation Techniques for Probiotics: Current Status and Future Prospects in Biomedical Applications.Nanomaterials (Basel, Switzerland) · 2023Review
- A bioinspired silica nanocomposite for enhanced multidrug-resistant bacteria treatment and wash-free imaging.Nanoscale advances · 2023Article
- Indane-1,3-Dione: From Synthetic Strategies to Applications.Molecules (Basel, Switzerland) · 2022Review
- Dynamic Progress in Technological Advances to Study Lipids in Aging: Challenges and Future Directions.Frontiers in aging · 2022Review
- Recent Advances in Aggregation-Induced Emission Active Materials for Sensing of Biologically Important Molecules and Drug Delivery System.Molecules (Basel, Switzerland) · 2021Review
- Discovery of a potent FKBP38 agonist that ameliorates HFD-induced hyperlipidemiaActa pharmaceutica Sinica. B · 2021Article
- Observation of crystallisation dynamics by crystal-structure-sensitive room-temperature phosphorescence from Au(I) complexes.Communications chemistry · 2020Article
- Synthesis and Spectrophotometric Analysis of 1-Azafluorenone Derivatives.Molecules (Basel, Switzerland) · 2020Article
- Supramolecular Hyaluronic Assembly with Aggregation-Induced Emission Mediated in Two Stages for Targeting Cell Imaging.ACS medicinal chemistry letters · 2020Article
- Light-Up Lipid Droplets Dynamic Behaviors Using a Red-Emitting Fluorogenic Probe.Analytical chemistry · 2020Article
- Pyrazolo-fused 4-azafluorenones as key reagents for the synthesis of fluorescent dicyanovinylidene-substituted derivatives.RSC advances · 2019Article
- Rational design and synthesis of yellow-light emitting triazole fluorophores with AIE and mechanochromic properties.Chemical communications (Cambridge, England) · 2019Article
- Recent Advances in Fluorescent Probes for Lipid Droplets.Materials (Basel, Switzerland) · 2018Review
- Consequences of a cosolvent on the structure and molecular dynamics of supramolecular polymers in water.Chemical science · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Photoactivatable probes for lipid droplets (LDs)-specific live-cell imaging are powerful tools for investigating their biological functions through precise spatial and temporal control. Ideal photoactivatable probes for LDs imaging require high concentration accumulation of fluorophores in LDs, simple synthetic procedures, and excellent photoactivation efficiency. However, it is difficult to overcome these challenges by conventional fluorophores due to aggregation-caused quenching (ACQ). In this study, a new class of photoactivatable and LDs-specific fluorescent probes was developed based on dihydro-2-azafluorenones, which can easily undergo photooxidative dehydrogenation reaction to afford 2-azafluorenones with aggregation-induced emission (AIE) properties. Dihydro-2-azafluorenones as photoactivatable and LDs-specific probes display significant advantages of excellent photoactivation efficiency and lack of self-quenching in the aggregated state, and are expected to have broad applications in study of biological functions of LDs' through light-controlled spatiotemporal imaging.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.