ArticleInternational journal of nanomedicine2018
Remineralization potential of nano-hydroxyapatite on enamel and cementum surrounding margin of computer-aided design and computer-aided manufacturing ceramic restoration.
Article in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 56 citations in OpenAlex.
- Efficacy of calcium hypophosphite toothpaste in remineralizing initial caries in vitro.BMC oral health · 2026Article
- Assessment of the remineralizing potential of nano-bioactive glass, nano-hydroxyapatite, and sodium fluoride on artificial carious lesions in primary teeth.BMC oral health · 2026Article
- Antibacterial and Bioregenerative Nanomaterials in Oral Health: From Material Design to Clinical Translation and Technological Trends.Journal of functional biomaterials · 2026Review
- Comparative Evaluation of the Shear Bond Strength of Composite to Remineralized Dentin: An In Vitro Study.Cureus · 2025Article
- Comparative Evaluation of Three Remineralization Agents-Bioactive Glass, Nanohydroxyapatite and Casein Phosphopeptide-amorphous Calcium Phosphate Fluoride-based Slurry on Enamel Erosion of Primary Teeth: AnInternational journal of clinical pediatric dentistry · 2025Article
- The potential of ceramic nanomaterials in preventive dentistry.Nanomedicine (London, England) · 2025Article
- Comparison of various chitosan-based in situ forming gels with sodium fluoride varnish for enamel biomineralization: an in-vitro pH cycling model.Scientific reports · 2024Article
- Polymer-Based Hydroxyapatite-Silver Composite Resin with Enhanced Antibacterial Activity for Dental Applications.Polymers · 2024Article
- Ion Release and Apatite Formation of Resin Based Pit and Fissure Sealants Containing 45S5 Bioactive Glass.Polymers · 2024Article
- Amelogenin-inspired peptide, calcium phosphate solution, fluoride and their synergistic effect on enamel biomimetic remineralization: an in vitro pH-cycling model.BMC oral health · 2024Article
- Nanoparticles and Their Antibacterial Application in Endodontics.Antibiotics (Basel, Switzerland) · 2023Review
- Novel antibacterial and apatite forming restorative composite resin incorporated with hydrated calcium silicate.Biomaterials research · 2023Article
- Potential Beneficial Effects of Hydroxyapatite Nanoparticles on Caries Lesions In Vitro-A Review of the Literature.Dentistry journal · 2023Review
- Ceramic Nanomaterials in Caries Prevention: A Narrative Review.Nanomaterials (Basel, Switzerland) · 2022Review
- Advanced materials for enamel remineralization.Frontiers in bioengineering and biotechnology · 2022Review
- Application of Selected Biomaterials and Stem Cells in the Regeneration of Hard Dental Tissue in Paediatric Dentistry-Based on the Current Literature.Nanomaterials (Basel, Switzerland) · 2021Review
- Evaluation the properties of orthodontic adhesive incorporated with nano-hydroxyapatite particles.The Saudi dental journal · 2021Article
- Advanced non-fluoride approaches to dental enamel remineralization: The next level in enamel repair management.Biomaterials and biosystems · 2021Review
- Article
- A Comparative Evaluation of Nanohydroxyapatite-Enriched Hydrogen Peroxide Home Bleaching System on Color, Hardness and Microstructure of Dental Enamel.Materials (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study investigates the effects of nano-hydroxyapatite (NHA) gel and Clinpro (CP) on remineralization potential of enamel and cementum at the cavosurface area of computer-aided design and computer-aided manufacturing ceramic restoration. MATERIALS AND
methodsThirty extracted human mandibular third molars were sectioned at 1 mm above and below the cemento-enamel junction to remove the cemento-enamel junction portions and replaced them with zirconia ceramic disks by bonding them to the crown and root portions with resin cement. The enamel and cementum with an area of 4×4 mm
resultsThe mean ± SD of Vickers microhardness for before demineralization, after demineralization, and after remineralization for enamel and cementum were 377.37±22.99, 161.95±10.54, 161.70±5.92 and 60.37±3.81, 17.65±0.91, 17.04±1.00 for the no treatment group; 378.20±18.76, 160.72±8.38, 200.08±8.29 and 62.58±3.37, 18.38±1.33, 27.99±2.68 for the NHA groups; and 380.53±25.14, 161.94±5.66, 193.16±7.54 and 62.78±4.75, 19.07±1.30, 24.46±2.02 for the CP groups. Analysis of variance indicated significant increase in microhardness of demineralized enamel and cementum upon the application of either NHA or CP (
conclusionNHA gel and CP were capable of remineralization of the enamel and cementum. NHA was more capable in the remineralization process than CP. NHA was extremely capable in the remineralization process for enamel and cementum surrounding the margin of the computer-aided design and computer-aided manufacturing ceramic.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.