Observational studyJournal of clinical monitoring and computing2019
Practical impact of a decision support for goal-directed fluid therapy on protocol adherence: a clinical implementation study in patients undergoing major abdominal surgery.
Observational study in Journal of clinical monitoring and computing, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assisted Versus Manual Goal Directed Fluid Therapy in Major Abdominal Surgery
HEMOdynamic Proactive Management During Cytoreductive Surgery and Intraperitoneal hyPErthermic Chemotherapy for Advanced Ovarian Cancer
The Use of the Hypotension Prediction Index (HPI) Combined With the Assisted Fluid Management (AFM) Software for Perioperative Hemodynamic Optimization in Patients Undergoing General Anesthesia.
Who cites it
21 citing papers in PubMed, 42 citations in OpenAlex.
- Decision support guided fluid challenges and stroke volume response during high-risk surgery: a post hoc analysis of a randomized controlled trial.Journal of clinical monitoring and computing · 2025Trial
- Assisted Fluid Management and Sublingual Microvascular Flow During High-Risk Abdominal Surgery: A Randomized Controlled Trial.Anesthesia and analgesia · 2025Trial
- Restrictive versus Decision Support Guided Fluid Therapy during Major Hepatic Resection Surgery: A Randomized Controlled Trial.Anesthesiology · 2024Trial
- Control of mean arterial pressure using a closed-loop system for norepinephrine infusion in severe brain injury patients: the COMAT randomized controlled trial.Journal of clinical monitoring and computing · 2024Trial
- Computer-assisted Individualized Hemodynamic Management Reduces Intraoperative Hypotension in Intermediate- and High-risk Surgery: A Randomized Controlled Trial.Anesthesiology · 2021Trial
- Implementation and learning curve in AI-assisted fluid management during abdominal oncologic surgery: a retrospective observational study.Journal of anesthesia, analgesia and critical care · 2026Article
- Anesthesia for cesarean delivery in the era of artificial intelligence: a narrative review.Journal of anesthesia, analgesia and critical care · 2026Review
- Efficacy of goal-directed fluid therapy monitored by pulse-pressure variation using a continuous noninvasive arterial pressure monitoring system (the CNAPArchives of medical science : AMS · 2025Article
- Closing the loop: automation in anesthesiology is coming.Journal of clinical monitoring and computing · 2024Article
- Goal-directed fluid therapy using uncalibrated pulse contour analysis and balanced crystalloid solutions during hip revision arthroplasty: a quality implementation project.Journal of orthopaedic surgery and research · 2023Observational
- A Pilot Study Assessing a Closed-Loop System for Goal-Directed Fluid Therapy in Abdominal Surgery Patients.Journal of personalized medicine · 2022Article
- Closed-Loop Controlled Fluid Administration Systems: A Comprehensive Scoping Review.Journal of personalized medicine · 2022Article
- The effect of compliance with a perioperative goal-directed therapy protocol on outcomes after high-risk surgery: a before-after study.Journal of clinical monitoring and computing · 2021Article
- Intraoperative hypotension during liver transplant surgery is associated with postoperative acute kidney injury: a historical cohort study.BMC anesthesiology · 2021Article
- Hydroxyethyl starch for perioperative goal-directed fluid therapy in 2020: a narrative review.BMC anesthesiology · 2020Review
- Shedding light on perioperative hemodynamic monitoring.Journal of clinical monitoring and computing · 2020Article
- Journal of Clinical Monitoring and Computing end of year summary 2019: hemodynamic monitoring and management.Journal of clinical monitoring and computing · 2020Review
- Automated systems for perioperative goal-directed hemodynamic therapy.Journal of anesthesia · 2020Review
- Feasibility of closed-loop titration of norepinephrine infusion in patients undergoing moderate- and high-risk surgery.British journal of anaesthesia · 2019Article
- Implementation of goal-directed therapy needs a boost, and it is called assisted fluid management.Journal of clinical monitoring and computing · 2019Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to assess the effects of using a real time clinical decision-support system, "Assisted Fluid Management" (AFM), to guide goal-directed fluid therapy (GDFT) during major abdominal surgery. We compared a group of patients managed using the AFM system with a historical cohort of patients (control group) who had been managed using a manual GDFT strategy. Adherence to the protocol was defined as the relative intraoperative time spent with a stroke volume variation (SVV) < 13%. We hypothesised that patients in the AFM group would have more time during surgery with a SVV < 13% compared to the control group. All patients had a radial arterial line connected to a pulse contour analysis monitor and received a 2 ml/kg/h maintenance crystalloid infusion. Additional 250 ml crystalloid boluses were administered whenever measured SVV ≥ 13% in the control group, and when the software suggested a fluid bolus in the AFM group. We compared 46 AFM-guided patients to 38 controls. Patients in the AFM group spent significantly more time during surgery with a SVV < 13% compared to the control group (median 92% [82, 96] vs. 76% [54, 86]; P < 0.0005), and received less fluid overall (1775 ml [1225, 2425] vs. 2350 ml [1825, 3250]; P = 0.010). The incidence of postoperative complications was comparable in the two groups. Implementation of a decision support system for GDFT guidance resulted in a significantly longer period during surgery with a SVV < 13% with a reduced total amount of fluid administered. Trial registration: Clinical Trials.gov (NCT03141411).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.