Evidence map›Paper›PMID 29779114›Full record

ArticleDoklady. Biochemistry and biophysics2018

General Sources of Dopamine As a Potential Morphogenic Factor in the Developing Striatum of Rats.

A I Kurtova, L K Dil'mukhametova, E R Mingazov, M V Ugrumov

Abstract read
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Article in Doklady. Biochemistry and biophysics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

A I KurtovaKoltzov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, 119334, Russia. reptofly@gmail.com.
L K Dil'mukhametovaKoltzov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, 119334, Russia.
E R MingazovKoltzov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, 119334, Russia.
M V UgrumovKoltzov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, 119334, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the striatum of rats at different stages of development, we determined the content of tyrosine hydroxylase and aromatic L-amino acids decarboxylase using double immunohistochemical labeling and estimated the expression level of their transcripts by real-time PCR. We found that, in different periods of development, there are three sources of dopamine in the striatum of rats: bienzymatic nerve fibers (throughout ontogeny), bienzymatic neurons (appear on day 18 of embryonic development), and monoenzymatic neurons (in adult animals). Dopamine, which is synthesized in the striatal neurons in the prenatal period, may function as a morphogenetic factor.

Indexed as

AnimalsAromatic-L-Amino-Acid DecarboxylasesDopamineGene Expression Regulation, EnzymologicMaleNeostriatumRatsRats, WistarTyrosine 3-MonooxygenaseAromatic-L-Amino-Acid DecarboxylasesDopamineTyrosine 3-Monooxygenase

Identifiers

PMID29779114

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.