Evidence map›Paper›PMID 29779106›Full record

ArticleDoklady. Biochemistry and biophysics2018

Modular Nanotransporter with P21 Fragment Inhibits DNA Repair after Bleomycin Treatment.

T R Kamaletdinova, A A Rosenkranz, A V Ulasov, Y V Khramtsov, A D Tsvetkova, G P Georgiev, A S Sobolev

Abstract read
PubMed Publisher
In one paragraph

Article in Doklady. Biochemistry and biophysics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

T R KamaletdinovaInstitute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia.
A A RosenkranzInstitute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia.
A V UlasovInstitute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia.
Y V KhramtsovInstitute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia.
A D TsvetkovaInstitute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia.
G P GeorgievInstitute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia.
A S SobolevInstitute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia. sobolev@igb.ac.ru.
Institute of Gene Biology · RULomonosov Moscow State University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modular nanotransporter (MNT) with C-terminal fragment of the p21 protein was synthesized and characterized, and its effect on DNA lesions was studied. This p21 fragment in MNT can significantly inhibit DNA repair in A431 human carcinoma cells after bleomycin treatment.

Indexed as

BleomycinCell Line, TumorCyclin-Dependent Kinase Inhibitor p21DNA RepairDrug CarriersHumansNanostructuresPeptide FragmentsBleomycinCDKN1A protein, humanCyclin-Dependent Kinase Inhibitor p21Drug CarriersPeptide Fragments

Identifiers

PMID29779106
OpenAlexW2804314375

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.