Evidence map›Paper›PMID 29779084›Full record

Observational studyDigestive diseases and sciences2018

Disease Activity Patterns Recorded Using a Mobile Monitoring System Are Associated with Clinical Outcomes of Patients with Crohn's Disease.

Eun Soo Kim, Sung Kook Kim, Byung Ik Jang, Kyeong Ok Kim, Eun Young Kim, Yoo Jin Lee, Hyun Seok Lee, Sang Gyu Kwak, Crohn’s and Colitis Association in Daegu-Gyeongbuk (CCAiD)

Abstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Digestive diseases and sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Remote Monitoring and Telemedicine in IBD: Are We There Yet?Current gastroenterology reports · 2020
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Eun Soo KimDivision of Gastroenterology, Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.
Sung Kook KimDivision of Gastroenterology, Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.
Byung Ik JangDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Yeungnam University College of Medicine, 317-1 Daemyung 5 Dong, Daegu, 705-703, Korea. jbi@med.yu.ac.kr.
Kyeong Ok KimDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Yeungnam University College of Medicine, 317-1 Daemyung 5 Dong, Daegu, 705-703, Korea.
Eun Young KimDivision of Gastroenterology, Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea.
Yoo Jin LeeDivision of Gastroenterology, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.
Hyun Seok LeeDivision of Gastroenterology, Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.
Sang Gyu KwakDepartment of Medical Statistics, Catholic University of Daegu School of Medicine, Daegu, Korea.
Crohn’s and Colitis Association in Daegu-Gyeongbuk (CCAiD)
Keimyung University · KRKyungpook National University · KRCatholic University of Daegu · KRYeungnam University · KRYeungnam University College

Funding

Keimyung University 2011National Research Foundation of Korea 2015R1D1A1A02062168
6 · The paper itself

Abstract

backgroundUsefulness of a mobile monitoring system for Crohn's disease (CD) has not been evaluated. We aimed to determine whether disease activity patterns depicted using a web-based symptom diary for CD could indicate disease clinical outcomes.

methodsPatients with CD from tertiary hospitals were prospectively invited to record their symptoms using a smartphone at least once a week. Disease activity patterns for at least 2 months were statistically classified into good and poor groups based on two factors in two consecutive time frames; the degree of score variation (maximum-minimum) in each frame and the trend (upward, stationary, or downward) of patterns indicated by the difference in the mean activity scores between two time frames.

resultsOverall, 220 (82.7%) and 46 (17.3%) patients were included in good and poor groups, respectively. Poor group was significantly more associated with disease-related hospitalization (p = 0.004), unscheduled hospital visits (p = 0.005), and bowel surgery (p < 0.001) during the follow-up period than good group. In the multivariate analysis, poor patterns [odds ratio (OR) 2.62, p = 0.006], stricturing (OR 4.19, p < 0.001) or penetrating behavior (OR 2.27, p = 0.012), and young age at diagnosis (OR 1.06, p = 0.019) were independently associated with disease-related hospitalization. Poor patterns (OR 4.06, p = 0.006) and an ileal location (OR 5.79, p = 0.032) remained independent risk factors for unscheduled visits. Poor patterns (OR 15.2, p < 0.001) and stricturing behavior (OR 9.77, p = 0.004) were independent risk factors for bowel surgery.

conclusionThe disease activity patterns depicted using a web-based symptom diary were useful indicators of poor clinical outcomes in patients with CD.

Indexed as

Mobile ApplicationsPatient Reported Outcome MeasuresSmartphoneAbdominal PainAdolescentAdultAppointments and SchedulesChi-Square DistributionCrohn DiseaseDefecationDigestive System Surgical ProceduresDisease ProgressionFemaleGastrointestinal MotilityHealth StatusHumansCrohn’s diseaseDisease activity patternSmartphone

Identifiers

PMID29779084
OpenAlexW2803454503

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.