Evidence map›Paper›PMID 29778260›Full record

ReviewInfectious disease clinics of North America2018

Treatment of Chronic Hepatitis C in Patients Receiving Opioid Agonist Therapy: A Review of Best Practice.

Brianna L Norton, Matthew J Akiyama, Philippe J Zamor, Alain H Litwin

Abstract readReview
In one paragraph

Review in Infectious disease clinics of North America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Frame Shift: Focusing on Harm Reduction and Shared Decision Making for People Who Use Drugs Hospitalized With Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  3. Outcomes of Low Barrier Hepatitis C Treatment in High Risk Populations From Primary Care.Journal of community hospital internal medicine perspectives · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Observational
  17. Observational
  18. Observational
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brianna L NortonDivision of General Internal Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, 3300 Kossuth Avenue, Bronx, NY 10467, USA. Electronic address: bnorton@montefiore.org.
Matthew J AkiyamaDivision of General Internal Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, 3300 Kossuth Avenue, Bronx, NY 10467, USA.
Philippe J ZamorDivision of Hepatology, Carolinas Healthcare Systems, 1025 Morehead Medical Drive, Suite 600, Charlotte, NC 28204, USA.
Alain H LitwinDivision of General Internal Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, 3300 Kossuth Avenue, Bronx, NY 10467, USA.

Funding

Intensive Models of HCV Care for Injection Drug UsersR01DA034086 · NIDA · CLEMSON UNIVERSITY · PI LITWIN, ALAIN HARRIS · 2012 to 2016
$3.7M
Adaptation and testing of a primary care HCV group medical treatment interventionK23DA039060 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI NORTON, BRIANNA · 2015 to 2019
$948k
Mentoring researchers on drug abuse and HIVK24DA036955 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI CUNNINGHAM, CHINAZO · 2014 to 2019
$911k
Advance Care Coordination and Enhanced Linkage and Retention Among Transitional Re-Entrants Living with Hepatitis C-The HCV-ACCELERATE TrialK99DA043011 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI AKIYAMA, MATTHEW · 2017 to 2018
$369k
NIDA NIH HHS K23 DA039060NIDA NIH HHS K24 DA036955NIDA NIH HHS K99 DA043011NIDA NIH HHS R01 DA034086
6 · The paper itself

Abstract

Injection drug use is the most common transmission route for hepatitis C. High rates of infection are observed among individuals on opioid agonist therapy. Although people who inject drugs carry the highest burden, few have initiated treatment. We present a comprehensive review of the evidence on the efficacy of HCV medications, drug-drug interactions, and barriers to and models of care. Studies have demonstrated comparable efficacy for individuals who are on opioid agonist therapy compared with those who are not. We propose that a strategy of treatment and cure-as-prevention is imperative in this population to curb the hepatitis C epidemic.

Indexed as

Analgesics, OpioidAntiviral AgentsClinical Trials as TopicDrug InteractionsHepacivirusHepatitis CHepatitis C, ChronicHumansPractice Guidelines as TopicSubstance Abuse, IntravenousAnalgesics, OpioidAntiviral AgentsBest practiceDirect acting antiviralsDrug-drug interactionsHepatitis C virusOpioid agonist therapy

Identifiers

PMID29778260
PMCPMC6022838

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.