Evidence map›Paper›PMID 29777500›Full record

ArticleJournal of behavioral medicine2018

Methamphetamine-associated dysregulation of the hypothalamic-pituitary-thyroid axis.

Deborah L Jones, Adam W Carrico, Suat Babayigit, Violeta J Rodriguez, Carlos Aguila, Mahendra Kumar

Abstract readComparative Study
In one paragraph

Article in Journal of behavioral medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Association of thyroid function with white coat hypertension and sustained hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2019
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Deborah L JonesDepartment of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, 1400 NW 10th Ave., Miami, FL, 33136, USA. djones@med.miami.edu.
Adam W CarricoDepartment of Public Health Sciences, Miller School of Medicine, University of Miami, Miami, USA.
Suat BabayigitDepartment of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, 1400 NW 10th Ave., Miami, FL, 33136, USA.
Violeta J RodriguezDepartment of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, 1400 NW 10th Ave., Miami, FL, 33136, USA.
Carlos AguilaDepartment of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, 1400 NW 10th Ave., Miami, FL, 33136, USA.
Mahendra KumarDepartment of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, 1400 NW 10th Ave., Miami, FL, 33136, USA.

Funding

University of Miami Developmental Center for AIDS Research (D-CFAR)P30AI073961 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Savita Pahwa · 2007 to 2026
$33.8M
HIV-1 Infection in Methamphetamine Abusers: Endocrine OutcomesR01DA031201 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI KUMAR, MAHENDRA · 2011 to 2015
$2.9M
Predictive Biomarkers of CVD Risk in Diverse HIV-1+ Cocaine AbusersR01DA034589 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI JONES, DEBORAH LYNNE, KUMAR, MAHENDRA · 2014 to 2018
$2.8M
NIAID NIH HHS P30 AI073961NIDA NIH HHS R01 DA031201NIDA NIH HHS R01 DA034589
6 · The paper itself

Abstract

Methamphetamine and HIV impair thyroid function, but few studies have investigated their combined effects on thyroid dysregulation. This study examined the associations of methamphetamine use alone and in combination with HIV on thyroid function among men in South Florida. Measures of thyroid function in methamphetamine-using, HIV-infected (METH+HIV+; n = 127) and HIV-negative (METH+HIV-; n = 46) men who have sex with men (MSM) were compared to non-methamphetamine-using, HIV-negative men (METH-HIV-; n = 136). Thyroid function was dysregulated in methamphetamine-using MSM, irrespective of HIV status. Both meth-using groups had greater odds of abnormal thyroid stimulating hormone levels and significantly higher mean free triiodothyronine (T3) levels. Elevated free T3 was associated with greater depressive symptoms. Overall, outcomes have important implications for assessment of thyroid function in methamphetamine users, particularly among those presenting with depression.

Indexed as

AdultAmphetamine-Related DisordersDepressionFloridaHIV InfectionsHomosexuality, MaleHumansHypothalamo-Hypophyseal SystemMaleMethamphetamineMiddle AgedPituitary-Adrenal SystemYoung AdultMethamphetamineDepressionHIVMethamphetamineThyroid hormonesTrauma

Identifiers

PMID29777500
PMCPMC6209523

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.