Evidence map›Paper›PMID 29777462›Full record

Observational studyJournal of neurovirology2018

A composite of multisystem injury and neurocognitive impairment in HIV infection: association with everyday functioning.

María J Marquine, Ilse Flores, Rujvi Kamat, Neco Johnson, Anya Umlauf, Scott Letendre, Dilip Jeste, Igor Grant, David Moore, Robert K Heaton

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of neurovirology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Antiretroviral Therapy Intensification for Neurocognitive Impairment in Human Immunodeficiency Virus.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Trial
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. The neurocognitive implications of depression and socioeconomic status in people with HIV.Journal of clinical and experimental neuropsychology · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

María J MarquineDepartment of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, San Diego, CA, 92093-0603, USA. mmarquine@ucsd.edu.
Ilse FloresNeuroscience Graduate Program, University of Southern California, Los Angeles, USA.
Rujvi KamatDepartment of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, San Diego, CA, 92093-0603, USA.
Neco JohnsonDepartment of Psychological and Brain Sciences, Washington University, Saint Louis, USA.
Anya UmlaufDepartment of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, San Diego, CA, 92093-0603, USA.
Scott LetendreDepartment of Medicine, University of California, San Diego, USA.
Dilip JesteDepartment of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, San Diego, CA, 92093-0603, USA.
Igor GrantDepartment of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, San Diego, CA, 92093-0603, USA.
David MooreDepartment of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, San Diego, CA, 92093-0603, USA.
Robert K HeatonDepartment of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, San Diego, CA, 92093-0603, USA.
University of California, San Diego · USUniversity of Southern California · USWashington University in St. Louis · US

Funding

STRUCTURAL NEUROIMAGING COREP30MH062512 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jennifer E Iudicello · 2001 to 2026
$50.4M
NEUROMOTORP01DA012065 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MASLIAH, ELIEZER · 1999 to 2009
$17.8M
California NeuroAIDS Tissue NetworkU24MH100928 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ACHIM, CRISTIAN L, MOORE, DAVID J · 2013 to 2023
$13.9M
NEUROAIDS TISSUE NETWORKR24MH059745 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GRANT, IGOR · 1998 to 2007
$13.2M
California NeuroAIDS Tissue Network (CNTN)U01MH083506 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GRANT, IGOR · 2008 to 2012
$8.1M
SDSU ADAR ProgramR25AG043364 · NIA · SAN DIEGO STATE UNIVERSITY · PI THEREASA A CRONAN · 2013 to 2026
$5.5M
Multi-Dimensional Successful Aging Among HIV-Infected AdultsR01MH099987 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JESTE, DILIP V., MOORE, DAVID J · 2013 to 2019
$3.8M
Risk and mechanisms of neurocognitive impairment in older HIV-infected HispanicsK23MH105297 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MARQUINE, MARIA · 2015 to 2018
$694k
NIA NIH HHS R25 AG043364NIDA NIH HHS P01 DA012065NIH HHS K23MH105297NIH HHS P01DA12065NIH HHS P30MH062512NIH HHS R01MH099987NIH HHS R24MH59745NIH HHS R25AG043364NIH HHS U01MH083506NIMH NIH HHS K23 MH105297NIMH NIH HHS P30 MH062512NIMH NIH HHS R01 MH099987NIMH NIH HHS R24 MH059745NIMH NIH HHS U01 MH083506NIMH NIH HHS U24 MH100928
6 · The paper itself

Abstract

The Veterans Aging Cohort Study (VACS) Index is a composite marker of multisystem injury among HIV-infected persons. We aimed to examine its cross-sectional association with functional outcomes, after considering neurocognitive impairment (NCI) and other well-established correlates of everyday functioning among HIV-infected persons. Participants included 670 HIV-infected adults (ages 18-76; 88% male; 63% non-Hispanic White; median current CD4 = 404 cells/mm

Indexed as

Quality of LifeAdolescentAdultAgedCognitive DysfunctionCohort StudiesCross-Sectional StudiesFemaleHIV InfectionsHumansMaleMiddle AgedSeverity of Illness IndexYoung AdultActivities of daily livingAIDSBiomarkersComorbidityEmployment statusNeurobehavioral manifestations

Identifiers

PMID29777462
PMCPMC6202221
OpenAlexW2803538078

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.