Evidence map›Paper›PMID 29777454›Full record

Observational studyJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2018

Improved Outcomes in 394 Pancreatic Cancer Resections: the Impact of Enhanced Recovery Pathway.

Vandana Agarwal, Martin Jose Thomas, Riddhi Joshi, Vikram Chaudhari, Manish Bhandare, Abhishek Mitra, Ashwin deSouza, Reshma Ambulkar, Shailesh V Shrikhande

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Effect of Frailty on Postoperative Outcomes Following Major Abdominal Surgeries: A Prospective Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  5. Article
  6. Global Perceptions on ERASWorld journal of surgery · 2023
    Article
  7. Observational
  8. Article
  9. Article
  10. Review
  11. Trends in Textbook Outcomes over Time: Are Optimal Outcomes Following Complex Gastrointestinal Surgery for Cancer Increasing?Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022
    Article
  12. Article
  13. Textbook outcomes in hepatobiliary and pancreatic surgery.World journal of gastroenterology · 2021
    Article
  14. Review
  15. Article
  16. Complications after Supramajor Gastrointestinal Surgery: Role of Enhanced Recovery after Surgery.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2020
    Review
  17. Article
  18. Article
  19. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vandana AgarwalDepartment of Anaesthesia, Critical Care and Pain, Tata Memorial Centre, HBNI, Dr Ernest Borges Marg, Parel, Mumbai, 400012, India. vandanachaukar@hotmail.com.ORCID 0000-0002-3593-0414
Martin Jose ThomasWestmead Hospital Sydney, Sydney, NSW, 2145, Australia.
Riddhi JoshiDepartment of Anaesthesia, Critical Care and Pain, Tata Memorial Centre, HBNI, Dr Ernest Borges Marg, Parel, Mumbai, 400012, India.
Vikram ChaudhariDepartment of Gastrointestinal Surgery, Tata Memorial Centre, HBNI, Dr Ernest Borges Marg, Parel, Mumbai, 400012, India.
Manish BhandareDepartment of Gastrointestinal Surgery, Tata Memorial Centre, HBNI, Dr Ernest Borges Marg, Parel, Mumbai, 400012, India.
Abhishek MitraNational Cancer Institute, Nagpur, Maharashtra, India.
Ashwin deSouzaDepartment of Gastrointestinal Surgery, Tata Memorial Centre, HBNI, Dr Ernest Borges Marg, Parel, Mumbai, 400012, India.
Reshma AmbulkarDepartment of Anaesthesia, Critical Care and Pain, Tata Memorial Centre, HBNI, Dr Ernest Borges Marg, Parel, Mumbai, 400012, India.
Shailesh V ShrikhandeDepartment of Gastrointestinal Surgery, Tata Memorial Centre, HBNI, Dr Ernest Borges Marg, Parel, Mumbai, 400012, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnhanced recovery (ER) pathway reduces morbidity and accelerates recovery. It is associated with reduced postoperative stay, morbidity, and costs. Feasibility and safety of ER programme has not been studied in developing countries. The objectives were to assess compliance with Enhanced Recovery After Surgery (ERAS) elements and to assess outcomes in pancreatic surgery.

methodsProspective study conducted from February 2014 to December 2016, following elective pancreatic cancer surgery. Team was educated prior to implementation of ERAS. Patients were followed up until 30 days postoperatively or discharge. Data was recorded regarding the compliance with the protocol, functional GI recovery, mobilisation, and postoperative morbidity and mortality.

resultsA total of 394 patients underwent surgery. Compliance with ER elements implemented was 84% (23-100%). Compliance > 80% with ER elements was observed in 278 patients (70.5%) and < 80% in 116 patients (29.5%). Patients with > 80% compliance have significantly lower major complications (28.7 vs. 44%, p = 0.001), mortality (2.1 vs. 6.8%, p = 0.021), and postoperative stay (11 (5-78) days vs. 15 (4-61) days, p < 0.001).

conclusionER programme is feasible and safe in resource and infrastructure limited lower middle-income country. Improved compliance was associated with reduced major complications, mortality, and shorter stay in patients undergoing pancreatic cancer surgery in high-volume centre.

trial registrationCTRI/2015/01/005393 ( www.ctri.nic.in ).

Indexed as

Patient ComplianceAdenocarcinomaAdolescentAdultAgedAged, 80 and overElective Surgical ProceduresFemaleHumansLength of StayMaleMiddle AgedPancreatic NeoplasmsPerioperative CarePostoperative ComplicationsPostoperative PeriodEnhanced recoveryPancreatic cancer resections

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.