Evidence map›Paper›PMID 29777304›Full record

ArticleEuropean journal of nutrition2019

No improvement in vitamin D status in German infants and adolescents between 2009 and 2014 despite public recommendations to increase vitamin D intake in 2012.

Clemens Kunz, Jürgen Hower, Anette Knoll, Kristin L Ritzenthaler, Thomas Lamberti

Open access · hybridAbstract read
In one paragraph

Article in European journal of nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Clemens KunzInstitute of Nutritional Sciences, Justus Liebig University Giessen, Wilhelmstr. 20, 35392, Giessen, Germany. clemens.kunz@uni-giessen.de.
Jürgen HowerPediatric Group Practice KIDS 4.0, Melllinghoferstr. 256, 45475, Mülheim, Germany.
Anette KnollAK Statistics, Kreppe 2, 85276, Pfaffenhofen, Germany.
Kristin L RitzenthalerHiPP Werk Georg Hipp OHG, Georg-Hipp-Straße 7, 85276, Pfaffenhofen, Germany.
Thomas LambertiPediatric Group Practice KIDS 4.0, Melllinghoferstr. 256, 45475, Mülheim, Germany.
Asklepios Klinik St. Georg · DEUniversity of Giessen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeVitamin D is a key component for the growth and development of children and adolescents, influencing a multitude of functions. Worldwide epidemiological studies have shown that minimum vitamin D blood levels of ≥ 20.0 ng/ml, often defined as vitamin D sufficiency by international and national nutrition and pediatric organizations, are often not met in practice. In 2012 the D-A-CH (Germany, Austria, Switzerland) nutrition societies increased their vitamin D intake recommendations fourfold from 200 IU (5 µg) to 800 IU (20 µg) per day. The outcome of this study will contribute to answering the question as to whether the new recommendations for increased vitamin D intake improve the highly prevalent vitamin D deficiency status in German children and adolescents.

methodsFor this 6-year study (January 2009-December 2014) carried out in Mülheim an der Ruhr, Germany, healthy children and adolescents (n = 1929, age range 1-17 years, median age 11.0 years, 46.9% female) consulting a pediatric group practice (KIDS4.0) were recruited. Serum 25(OH)D determinations were performed using a competitive chemoluminescence immunoassay (CLIA, DiaSorin).

resultsThe median serum vitamin D values for each year from 2009 to 2014 were 18.4, 13.0, 20.8, 16.4, 19.4 and 14.9 ng/ml. The summarized median 25(OH)D serum concentrations between the two time periods 2009-2012 and 2013-2014 after increasing recommendations for vitamin D intake did not show a significant difference (17.0 versus 16.8 ng/ml).

conclusionsThe increased D-A-CH recommendations for vitamin D intake had no influence on vitamin D levels in children and adolescents. The prevalence of vitamin D deficiency has not changed compared to previous studies.

Indexed as

Recommended Dietary AllowancesAdolescentChildChild, PreschoolFemaleGermanyHumansInfantMaleNutrition SurveysVitamin DVitamin D DeficiencyVitamin DAdolescentsChildrenGerman infantsPrevalenceVitamin D deficiency

Identifiers

PMID29777304
PMCPMC6561984
OpenAlexW2803236474

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.